We evaluated long-term results of De Vega annuloplasty measured by cylindrical sizers for functional tricuspid regurgitation (FTR) and analyzed the impact of measured annular size on the late recurrence of tricuspid valve regurgitation. Between 2001 and 2011, 177 patients (57.9±10.5 yr) underwent De Vega annuloplasty for FTR. Three cylindrical sizers (actual diameters of 29.5, 31.5, and 33.5 mm...

To the Editor: We read with great interest the article by Kim and colleagues. First, we would like to congratulate the authors for their study investigating relatively underestimated or neglected valvular disease; mild to moderate functional tricuspid regurgitation (FTR). Although the latest guidelines do not recommend any intervention to this patient population, numerous long-term follow-up st...

We consider power portfolio optimization of real and contractual assets, including derivative instruments in a multi-period setting. A model is introduced that incorporates fixed transmission rights in a three-node unidirectional network in order to evaluate the significance of transmission constraints. We use data from the PJM, which is located in the eastern United States for model implementa...

OBJECTIVES Functional tricuspid regurgitation (FTR) is generally caused by the dilation of the tricuspid annulus (TA) and the tethering of tricuspid leaflets; however, it also occurs in patients without dilatation of the TA. The aim of this study was to develop and to use a four-dimensional tracking system, utilizing cardiac magnetic resonance imaging (MRI), and to assess TA flexibility in pati...

OBJECTIVE Recently, failure to rescue (FTR; death following major complication) has been shown to be a primary driver of mortality in highly morbid operations. Establishing this relationship for open and endovascular repair of abdominal aortic aneurysms may be a critical first step in improving mortality following these procedures. We sought to examine the relative contribution of severe compli...

IMPORTANCE Disparities in operative mortality due to socioeconomic status (SES) have been consistently demonstrated, but the mechanisms underlying this disparity are not well understood. OBJECTIVE To determine whether variations in failure to rescue (FTR) contribute to socioeconomic disparities in mortality after major cancer surgery. DESIGN, SETTING, AND PARTICIPANTS We performed a retrosp...

We have previously shown that voluntary wheel running (VWR) attenuates, whereas forced treadmill running (FTR) exacerbates, intestinal inflammation and clinical outcomes in a mouse model of colitis. As the gut microbiome is implicated in colitis, we hypothesized that VWR and FTR would differentially affect the gut microbiome. Mice (9-10/treatment) were randomly assigned to VWR, FTR, or sedentar...

Translational readthrough (TR) has come into renewed focus because systems biology approaches have identified the first human genes undergoing functional translational readthrough (FTR). FTR creates functional extensions to proteins by continuing translation of the mRNA downstream of the stop codon. Here we review recent developments in TR research with a focus on the identification of FTR in h...