نتایج جستجو برای: fibrosarcomatous dermatofibrosarcoma protruberans
تعداد نتایج: 763 فیلتر نتایج به سال:
PURPOSE To report on imatinib mesylate (IM) in patients with metastatic dermatofibrosarcoma protuberans (DFSP)/fibrosarcomatous (FS)-DFSP and on the impact of the treatment on tumor biology. EXPERIMENTAL DESIGN Ten consecutive patients treated with IM from 2007 to 2015 for a metastatic relapse from DFSP/FS-DFSP were identified. FISH analysis for COL1A1-PDGFB was performed. Two IM-treated and ...
Abstract Background Fibrosarcomatous dermatofibrosarcoma protuberans (FS-DFSP) is a form of tumor progression (DFSP) with an increased risk metastasis and recurrence. Few studies have compared the clinicopathological features FS-DFSP conventional DFSP (C-DFSP). Objectives To better understand epidemiological characteristics FS-DFSP. Methods We conducted cohort study 221 patients diagnosed built...
Introduction: Dermatofibrosarcoma protuberans (DFSP) is an intermediate and slow-growing sarcoma, arising most commonly in the trunk extremities rarely breast. It may be recurrent, but metastasis rare. Excision with good resection margins reduces rate of recurrence. Case Presentation: A 28-year-old lady presented a painless lump left breast 16 years duration. Examination revealed ulcerated firm...
Dermatofibrosarcoma protuberans (DFSP) is an aggressive PDGFB-dependent cutaneous sarcoma characterized by infiltrative growth and frequent local recurrences. Some DFSP progress to a higher-grade fibrosarcomatous form, with rapid growth and increased risk of metastasis. Imatinib provides clinical benefit in approximately 50% of patients with unresectable or metastatic DFSP. However, efficacious...
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