We have used Horseradish peroxidase to investigate the pathways taken by Xenopus optic fibres regenerating from normal and electrophysiologically-confirmed compound eyes to the optic tectum. Optic fibres, when sectioned near the chiasma, regenerate up both sides of the diencephalon to both tecta. We have therefore been able, by using animals in which one eye had or had not been removed at early...

The distribution of muscle fibres classified on the basis of their content of different myosin heavy chain (MHC) isoforms was analysed in muscle biopsies from the gluteus medius of adult untrained horses by correlating immunohistochemistry with specific anti-MHC monoclonal antibodies and standard myofibrillar ATPase (mATPase) histochemistry. Percutaneous needle biopsies were taken at 3 depths (...

OBJECTIVE To describe the distribution of elastic fibres in the developing male urethra and to provide stereological data of the concentration of elastic fibres in the human urethra. MATERIALS AND METHODS Urethras were obtained from 10 fresh normal human fetuses at 15-36 weeks of gestation. A place-matched spongy urethra of a 27-year-old normal adult man was also analysed. Samples were fixed ...

In juvenile Xenopus retinotopic fibre order in the optic tract near the chiasma was investigated by labelling small groups of optic fibres from peripheral retina with HRP. This selective fibre labelling with HRP was combined with autoradiography following administration of tritiated thymidine to the eye, so that the HRP-labelled fibres could be located within the borders of the optic tract. Fib...

To be able to perform swift and powerful movements, ant mandible closer muscles are composed of two subpopulations of muscle fibres: fast fibres for rapid actions and slow fibres for forceful biting. All these fibres attach to a sturdy and complex apodeme which conveys force into the mandible base. Fast muscle fibres attach directly to the apodeme. Slow fibres may attach directly or insert at i...

Damaged skeletal muscle fibres are replaced with new contractile units via muscle regeneration. Regenerating muscle fibres synthesize functionally distinct isoforms of contractile and regulatory proteins but little is known of their functional properties during the regeneration process. An advantage of utilizing single muscle fibre preparations is that assessment of their function is based on t...

Antisera raised against neuron specific enolase (NSE), substance P, vasoactive intestinal peptide (VIP) and tyrosine hydroxylase (TH) were used to reveal nerve fibres in the wall of the canine small and large intestine. The circular muscle of the colon was innervated by nerve fibre bundles that ran parallel to the muscle throughout its thickness. A plexus of fibre bundles was found against the ...

induction of cancer. It is important that sufficient numbers of fibres from each sample to be tested for carcinogenicity be measured using methods that allow detection of both submicroscopie and microscopic fibres, so that the number of fibres of specific dimensional categories per unit mass can be calculated. When characterizing exposures to man-made mineraI fibres, it is necessary to specify ...

Distinct subsets of sensory nerve fibres are involved in mediating mechanical and thermal pain hypersensitivity. They may also differentially respond to analgesics. Heat-sensitive C-fibres, for example, are thought to respond to μ-opioid receptor (MOR) activation while mechanoreceptive fibres are supposedly sensitive to δ-opioid receptor (DOR) or GABAB receptor (GABABR) activation. The suggeste...

changes in moisture content and temperature can perturb both stiffness and strength and as such the impact resistance of composite structures. in this paper, the pre-notched basalt fibre reinforced epoxy (bfre) composite specimens are studied under charpy impact loads in order to investigate the changes in impact energy absorption (fracture toughness) with different kinds of aging conditions. t...