Haemostasis is the process of forming clots in the walls of damaged blood vessels to prevent abnormal bleeding and to maintain intravascular blood in a fluid state. Fenugreek is largely universal staple herb, popular throughout history and it has been consumed for treatment of different disorders. We aimed to study the possible anticoagulant effect of Fenugreek aqueous extract in vitro by using...

Due to fenugreek based on different grown environment has vital differences in quality and physiological efficacy, this study focused on classification and identification of fenugreek seeds from different production areas using Fourier Transform Infrared (FT-IR) Spectroscopy coupled with cluster analysis. Chemometrics fequencies at 1800400 cm were exploited for the establishment of all chemomet...

BACKGROUND AND AIM Fenugreek is a herb that is widely used in cooking and as a traditional medicine for diabetes in Asia. It has been shown to acutely lower postprandial glucose levels, but the long-term effect on glycemia remains uncertain. We systematically reviewed clinical trials of the effect of fenugreek intake on markers of glucose homeostasis. METHODS PubMed, SCOPUS, the Cochrane Tria...

The prevalence of type 2 Diabetes (NIDDM) and obesity have been increasing at epidemic proportions worldwide. It has become a major global health problem in economically developed as well as in countries undergoing rapid economic expansion. Indians due to their genetic preponderance, diet and life style patterns suffer most from diabetic diseases. Evidence showing that even Indian migrants have...

Methods Female C3H/HeJ mice were gavaged at days 0, 1, 2, 7, and 21 with fenugreek in doses ranging from 0.1 mg to 10 mg. Cholera toxin (CT) was used as an adjuvant (10 μg/mouse). The mice were euthanized on day 28, and sera were analysed for fenugreek-specific IgE using the heterologous passive cutaneous anaphylaxis assay. Based on this dose-response experiment, twenty four mice were gavaged w...

Fenugreek is a common herb possessing several bioactive components including diosgenin. Here, dietary fenugreek seed flour and diosgenin were evaluated on a model of endothelium-dependent vasorelaxation by abdominal aortas isolated from rats receiving high-fat, high-sugar diet (HFHSD). 60 male Wistar rats were randomized into six groups: (i) negative control getting conventional rat feed regime...

BACKGROUND/OBJECTIVE The purpose of the present study was to evaluate the effect of fenugreek seed extract in combination with swimming exercise compared to glibenclamide consumption on type 2 diabetic rats. DESIGN The acute toxicity test was carried out to choose the safe doses and identify the toxicity effects of the fenugreek seed extract. To investigate the hypoglycemic effect of the extr...

This study determined the effects of fenugreek on postprandial plasma glucose (PPG) and satiety among overweight and obese individuals. Fourteen subjects were studied in the morning after overnight fasts on four separate occasions. Glycaemic responses elicited by 50 g carbohydrate portions of white bread and jam with or without 5.5 g of fenugreek and fried rice with or without 5.5 g fenugreek w...

Fenugreek (Trigonella foenum-graecum) seeds were extracted in 80% methanol to examine the content of various potent antioxidant compounds and their influence on in-vitro oxidation of biomolecules i.e. amount. proteins, lipids and DNA. Fenugreek extract had polyphenols (9.47±0.10 mg GAE/g dry seeds) as major antioxidant principle. Gallic acid (170.335μg), caffeic acid (164.550 μg), ellagic acid ...