objective(s): several researchers have reported the relationship between infertility in male and varicocele for so many years but the implication of varicocele in female patients is remains elusive. here, we aim to examine the effects of unilateral varicose ovarian vein on antioxidant capacity and oocyte quality of rat ovary after the experimental creation of varicocele in female rats. material...

Background: Doxorubicin is an effective chemotherapeutic drug, but its toxic potential limits use. Aim: To study the effects of doxorubicin on relative tissue weight index and hepatic central vein diameter in albino rats. Study Design: Experimental Place Duration study: was conducted 20 adult rats both male female gender animal house Anatomy department, (PGMI) Lahore, Pakistan April 2019. Mater...

This study reports the presence of a high molecular weight protein (Bengalin) from the Indian black scorpion (Heterometrus bengalensis) venom having antiosteoporosis activity in experimental osteoporosis developed in female albino Wister rats. Bengalin was purified through DEAE-cellulose ion exchange chromatography and high performance liquid chromatography. The molecular weight of the Bengalin...

Background: The current study was conducted at the Department of Veterinary Pharmacology and Toxicology to assess impact Emblica officinalis on oxidative stress produced by sub-acute enrofloxacin exposure in albino rats. Methods: Albino rats weighing 200-300 gram were given orally through gavage needle blood samples taken via capillary tube 28th day experiment analysed using laboratory procedur...

OBJECTIVE To see the effect of chloroquine on liver weight of developing albino rats. METHODS Twenty four pregnant female albino rats were used and divided in 4 groups. They were kept in Animal House of Post Graduate Medical Institute, Lahore. Total gestational period in rats ranges from 20-22 days, which in this study was divided into three trimesters, each of seven days. Using oral dose of ...

Male and female albino rats given different oral doses (0.75, 2.5, 5.0 and 0.25, 0.75, 1.5 mg/kg/D) of endosulfan respectively for a period of 30 days elicited signs of toxicity such as hyperexcitability, tremor, dyspnea and salivation for a brief period. At the tested dose levels, endosulfan produced no significant change in the organ body weight ratio, biochemical, histological, haematologica...

This study has been undertaken to investigate the effect of Ehretia microphylla L._ on folliculogenesis, relative ovary and uterus weight and the number of ovarian surface follicles in female Wistar albino rats. The study consisted of 24 female wistar rats that were divided into four groups. Group-I 0.5 ml distilled water, Group II, III and IV were orally administered with powdered form of E. m...

The use of nitrogen mustards as chemotherapeutic agents in the treatment of certain neoplastic diseases has been well established by a large number of workers (Montgomery, 1959; Creech, Breuninger, Hankwitz, Polsky & Wilson, 1960; Ross, 1962). A large number of different compounds have been screened in various test systems in vitro and in vivo for anticancerous, antibacterial, antimicrobial and...

The effects of Delonix regia extract (d200mg, d300mg, and d400mg), metformin (m8.3mg, m12.5mg and m16.5mg), pioglitazone (p0.5mg, p0.7mg and p0.9mg) and combined formulation of metformin and extract (m6.25d150mg) on glycated hemoglobin status in streptozotocin-induced diabetic Albino wistar rats. Diabetic status of these rats was assessed by estimating fasting blood glucose levels. A total of 1...