First report on the production of protease through fed batch cultivation using co-culture of Pseudomonas putida and Staphylococcus aureus from a crude carbon source, banana peel. Batch production by using synthetic medium, impact of some of the process parameters on cell growth and alkaline protease activity was investigated and the optimized values were found to be inoculum size of 5 % (v/v), ...

Background Lignin valorization has recently been considered to be an essential process for sustainable and cost-effective biorefineries. Lignin represents a potential new feedstock for value-added products. Oleaginous bacteria such as Rhodococcus opacus can produce intracellular lipids from biodegradation of aromatic substrates. These lipids can be used for biofuel production, which can potenti...

On-line monitoring of batch processes using multi-way independent component analysis has attracted much attention in both academia and industry. This paper focuses on two knotty issues concerning selecting dominant independent components without a standard criterion and determining the control limits of monitoring statistics in the presence of non-Gaussian distribution. To optimize the number o...

Erythromycin production is clearly enhanced by the addition of vegetable oils. However,whether this positive effect is brought about by the triglyceride or non-triglyceride fraction, isnot clear. The non-triglyceride portions of the oils accumulate in the waste during the refiningprocess leaving mainly triglycerides in the refined oil. In this research, sub-fractions of soybeanoil, including le...

erythromycin production is clearly enhanced by the addition of vegetable oils. however,whether this positive effect is brought about by the triglyceride or non-triglyceride fraction, isnot clear. the non-triglyceride portions of the oils accumulate in the waste during the refiningprocess leaving mainly triglycerides in the refined oil. in this research, sub-fractions of soybeanoil, including le...

The fed-batch fermentation of glycerol to 1,3-propanediol by Klebsiella pneumoniae displayed an unusual dynamic behavior that can be clearly divided into four distinct phases according to cell growth and CO(2) evolution rate. Metabolism changed significantly during the different phases as reflected by the varied specific rates of substrate consumption and product formation. An assay of activiti...

Industrial fermentation systems are often operated in fed-batch mode [1], however this mode of operation can make planning and scheduling challenging due to batch-to-batch variation. There is natural variability in the length of the batch phase due to biological variations, in addition to batch-to-batch variations in initial process conditions from raw materials [2]. These affect the reproducib...