Fig.4: Temperature changes of the hottest voxel in 2D cheese experiments. While the conventional sequence (magenta) underestimated temperatures due to the presence of fat, the present method (green) suppressed fat and reduced imaging time by 8-fold. Green line is the result of temporal average over a sliding window of 8 time frames. Fig.2: Excitation profile in a cheese phantom. The distance be...

Introduction: The routine use of a calibration phantom that fits easily into a breast coil could provide the basis for standardization and patient-specific calibration of breast MRI. Here, we use a phantom to correct the variable flip angles in a T1 measurement. This increases the accuracy of T1 and contrast media concentration measurements obtained with a clinically employed T1-weighted dynami...

PURPOSE To evaluate the effect of the hybrid RARE (rapid acquisition with relaxation enhancement) readout, commonly coupled to inversion-recovery pulse sequences, on the null inversiton time (TI) of fluid and fat using both phantoms and human volunteers. METHODS Two phantoms, simulating fat (phantom A) and cerebrospinal fluid (phantom B), respectively, were imaged using a fast inversion-recov...

Noninvasive biomarkers of intracellular accumulation of fat within the liver (hepatic steatosis) are urgently needed for detection and quantitative grading of nonalcoholic fatty liver disease, the most common cause of chronic liver disease in the United States. Accurate quantification of fat with MRI is challenging due the presence of several confounding factors, including T*(2) decay. The spec...

OBJECTIVE In a clinical setting, lipoma can sometime show low signal intensity on susceptibility-weighted imaging (SWI) mimicking hemorrhage. The purpose of this study was to evaluate the fat-water interface chemical-shift artifacts between SWI and T2*-weighted imaging with a phantom study and evaluate SWI in lipoma cases. MATERIALS AND METHODS SWI, magnitude, high-pass filtered phase, and T2...

introduction: in diagnostic and therapeutic procedures, dosimetric studies are performed on the dosimetric systems in order to comply the radiation safety standards. monte carlo methods are used due to the high complexity and cost of patient-specific phantom construction. the high complexity of the digitized phantoms greatly increases the time and computational task of the monte carlo calculati...

R. Nezafat, J. A. Derbyshire, R. Ouwerkerk, M. Stuber, E. R. McVeigh Lab of Cardiac Energetics, Division of Intramural Research, NHLBI, NIH, DHHS, Bethesda, MD, United States, Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States, Radiology, Johns Hopkins University, Baltimore, MD, United States Introduction: T2 magnetization preparation (T2 Prep) and spectrally selecti...

The aim of this document is to define the quality assurance (QA) methods for scanners using the ice-water phantom and the corresponding software developed within the IMI QuIC-ConCePT project, for the upcoming ‘BOS2’ trials. The outlined methods are what we consider to constitute the best use of currently available data following our recent papers [1] [2] in which we studied ADC (apparent diffus...

Introduction: The present study is aimed to design and develop a tissue-equivalent pelvic phantom, mimicking the Indian female pelvic dimensions by means of locally available and cost-effective tissue substitutes having equivalent radiological properties. Materials and Methods: For the purpose of the study, the real female pelvic bones were embedded for preparation. Paraffin wax, Aloe-vera powd...