Patients with Fanconi anemia (FA) are prone to develop malignancies at an early age. Besides hematologic malignancies, squamous cell carcinomas in the anogenital region and head and neck are also frequently found in these patients. The aim of this study was to generate a panel of head and neck squamous cell carcinoma (HNSCC) cell lines and xenografts of FA HNSCC, and to characterize these cell ...

BACKGROUND Abnormal metabolism of fatty acids (FA) is considered to play a role in human cancers, including esophageal cancer (EC). Nevertheless, there have been only a few studies dealing with the influence of the chemotherapy or radiotherapy on the plasma FA profiles. In this work we compared FA in plasma phosphatidylcholine (PC) of the patients with squamous EC and healthy subjects and inves...

BACKGROUND Dairy products are a major contributor to dietary SFA. Partial replacement of milk SFA with unsaturated fatty acids (FAs) is possible through oleic-acid rich supplementation of the dairy cow diet. To assess adherence to the intervention of SFA-reduced, MUFA-enriched dairy product consumption in the RESET (REplacement of SaturatEd fat in dairy on Total cholesterol) study using 4-d wei...

The migrant black-tailed godwit (Limosa limosa) traditionally used natural wetlands in the Iberian Peninsula to prepare for migratory flights by feeding mainly in estuaries. In recent decades, this species has become increasingly dependent on rice fields, thereby relying on a plant-based diet for fuelling. Dietary fatty acids (FA) seem to be determinant to the composition of accumulated subcuta...

There are very few studies in ruminants characterizing mammary and adipose tissue (AT) expression of genes and gene networks for diets causing variations in milk fatty acid (FA) composition without altering milk fat secretion, and even less complementing this information with data on tissue FA profiles. This work was conducted in sheep in order to investigate the response of the mammary gland a...

The present work intends to obtain and characterize a milk by-product: the human whey (HW), in order avoid excessive disposal of (HM). characterization was performed through analyzes chemical composition fatty acids (FAs) triacylglycerol (TAG) lipid profile. results indicated that altered significantly after HW obtained, except for percentage ash carbohydrates. About FA composition, it observed...

A novel geometric framework for decomposition of tensor distance into shape and orientation distances is proposed. We show that such shape distance leads to the development of a novel and robust anisotropy measure that reveals strikingly superior white matter profile of DT-MR brain images than fractional anisotropy (FA) and analytically show that it has a higher signal to noise ratio than FA. U...

A routine monitoring for subacute ruminal acidosis (SARA) on the individual level could support minimization of economic losses and ensuring animal welfare in dairy cows. The objectives this study were (1) to develop a SARA risk score (SRS) by combining information from different data acquisition systems generate an integrative indicator trait, (2) investigation associations SRS with feed analy...

BACKGROUND/AIMS The fatty acid profile in plasma lipids contributes to the increase of plasma high sensitivity C-reactive protein (hsCRP), a marker of inflammation and predictor of cardiovascular risk. The aim of this study was to examine the relationship between specific fatty acids (FA) of serum lipids and serum hsCRP in morbidly obese woman. METHODS The study included 16 morbidly obese (me...