objective(s):to investigate the effects of local mild hypothermia on the expression of fas, fasl and mmp-3 after cerebral ischemia-reperfusion in rats. materials and methods:male wistar rats were divided into sham-operated group (sham), normothermia group (nt), and hypothermia group (ht). mcao/r model was established by longa’s method, and reperfusion was allowed after 2 hr occlusion. mild hypo...

background: b re a st con s er v i n g surg e ry ( b c s ) f o l l owed b y loc a l rad i ot h e ra p y is the standard t r eatment for e a rly sta g e of breast cancer. margin stat u s may have an important impact on local recurren c e and over a ll s u rvival of patients treated with bcs, but this h a s not b een defined adequately. in this study, we in ve stigated the rela t io n ship betwee...

platelet aggregation beta amyloid main causes inflammation of neurons in alzheimer’s disease. in fact, creating this inflammation due to inappropriate actions in blood brain barrier (bbb) and astrocyte and microglia during the last century that studies conducted in this case nothing has been found. the only thing that can be done to prevent and reduce pro-inflammatory factors such as cytokines ...

sulfonamides are the first effective chemotherapeutic agents used for several years to cure or prevent systemic bacterial infections. in addition, this agents showed anti-carbonic anhydrase and cause cell cycle perturbation in the g1 phase, disruption of microtubule assembly, suppression of the transcription activator nf-y, angiogenesis and matrix metalloproteinase (mmp). in recent years, novel...

precise application of the n fertilizer rate is critical to achieve maximum yield. in major regions, empirical methods were used for determining n fertilizer requirement. these methods cannot take into account variation in management and environmental conditions on determining fertilizer requirement. crop simulation models can provide an alternative means of determining the optimum crop n requi...

background: a lot of women die each because of unwanted pregnancies and unsafe abortion. according to importance of unwanted pregnancies, the purpose of the current study is to determine prevalence of unwanted pregnancy and its related factors in interruption method users in gorgan health-care centers in 2010. methods: in this descriptive-analytical study, 339 eligible women that were under sup...