Biliary Atresia (BA) is a well-known entity and can present with multiple congenital anomalies. BA is one of the most common conditions in which pediatric liver transplant is performed. Identification of Biliary atresia with situs inversus (SI) has not been documented in Pakistan. We report two such cases. First was an eighty-day-old baby boy, icteric from day of birth. On further evaluation ha...

OBJECTIVE To report a case of severe dystrophic calcification in maxillary sinus of a child with liver transplantation and dental organs pigmented by hyperbilirubinemia. CASE DESCRIPTION female patient, 12 years old, with liver transplantation performed at the age of 7 due to extrahepatic biliary atresia (EHBA). The patient was receiving the immunosuppressant tacrolimus (2 mg daily). Intraora...

Nonvisualization of the gallbladder during the second trimester of pregnancy should prompt concern for biliary atresia. A normal-sized gallbladder with irregular and crenelated wall associated with a cyst of the extrahepatic tract should raise concern for cystic biliary atresia.

intrahepatic bile ducts in the vicinity of the porta hepatis in biliarv atresia. Tohokuj Exp Med 1976;118: 199-207. 3 Gautier M, Eliot N. Extrahepatic biliary atresia. Morphological study of 98 biliary remnants. Arch Pathol Lab Med 1981;105:397-402. 4 Mowat AP, Psacharopoulos HT, Williams R. Extrahepatic biliary atresia versus neonatal hepatitis. A review of 136 prospectively investigated infan...

Case 1. The elder of two sibs, this boy was born on May 21, 1965 to unrelated healthy parents aged 29 (mother) and 30 years (father). Birthweight was 2820 g.; delivery was by forceps. His mother had 'influenza' between the fifth and sixth months of the pregnancy which had been otherwise normal. There was no previous foetal loss. Four generations of the family, comprising, in addition to the par...

BACKGROUND The etiologies of conjugated hyperbilirubinemia in infancy are diverse. OBJECTIVE Determine the prevalence rates of the specific etiologies of conjugated hyperbilirubinemia in infancy. DATA SOURCES EMBASE and Pubmed were searched electronically and the bibliographies of selected studies were search manually. The search was conducted independently by two authors. STUDY SELECTION...

The objective of this study was to study etiologies and outcome of neonatal cholestasis in Thai infants. The medical records of infants aged less than 3 months with the diagnosis of neonatal cholestasis in Department of Pediatrics, Siriraj Hospital from 1993 to 2004 were retrospectively reviewed. The etiologies were diagnosed by history, physical examination, and proper investigations. There we...

introduction: early differentiation of biliary atresia from neonatal hepatitis is of utmost importance, since on time surgery of biliary atresia significantly improves the outcome. hepatobiliary scintigraphy is an integral part of diagnosis work-up of these patients; however its specificity for diagnosis of biliary atresia is suboptimal. in this study we evaluated the value of ursodeoxycholic a...

Background: Extrahepatic biliary atresia (EHBA) is a chronic obstructive cholangiopathy of infancy with obscure aetiology. I recently reported unanimous strong immunohistochemical staining against neutrophil elastase in EHBA liver biopsies, with variable degrees of fibrosis, and variable CD14+ monocytes intensity staining. Neutrophil inflicted cellular damage is a crucial step for regeneration ...