: Desmoid tumor (DT) is a fibroblastic proliferation arising in soft tissue characterized by localized infiltrative growth with an inability to metastasize but tendency recurrence. Nuchal-type fibromas are benign lesions that usually developed the posterior neck. The development of these neoplasms can be associated hereditary cancer predisposition syndrome, mainly familial adenomatous polyposis...

Adrenal hemangioma is an uncommon benign vascular tumor that is often discovered incidentally. It has never been reported in association with familial adenomatous polyposis. We report a case of a 60-year old man with a history of familial adenomatous polyposis, in whom a huge retroperitoneal cyst of 18x17 cm was discovered during routine radiologic evaluation. Because of the impossibility of ru...

AIM Our aim was to perform a prospective evaluation of the frequency and diagnostic consequences of extracolonic findings at multidetector array computed tomography colonography (MDCTC) in asymptomatic patients undergoing surveillance for former colorectal polyps or cancer. PATIENTS AND METHODS Seventy five consecutive patients undergoing surveillance for former colorectal cancer (CRC) or lar...

Present knowledge of systemic lupus erythematosus, albeit scarce, has been accumulated slowly since its original description to its present recognition as a complex systemic disease responsible for a number of syndromes previously considered unrelated. The true incidence of systemic lupus erythematosus, though still unknown, evidently is much greater than was realized before the discovery of th...

Present knowledge of systemic lupus erythematosus, albeit scarce, has been accumulated slowly since its original description to its present recognition as a complex systemic disease responsible for a number of syndromes previously considered unrelated. The true incidence of systemic lupus erythematosus, though still unknown, evidently is much greater than was realized before the discovery of th...

Gardner's syndrome is characterized by colonic polyps, osteomas of the skull and the mandible, and soft tissue tumors. Patients with this syndrome can also develop extracolonic manifestations such as periampullary tumors and desmoid tumor of the abdomen. We report a 36 year-old female with Gardner's syndrome and recurrent desmoid tumors of the abdomen, presenting with fever and malaise for 2 da...

Familial adenomatous polyposis (FAP) is an inherited disorder that represents the most common gastrointestinal polyposis syndrome. Germline mutations in the APC gene were initially identified as responsible for FAP, and later, several studies have also implicated the MUTYH gene as responsible for this disease, usually referred to as MUTYH-associated polyposis (MAP). FAP and MAP are characterize...

Goel, K. M., and Shanks, R. A. (1973). Archives of Disease in Childhood, 48, 337. Long-term prognosis of children with ulcerative colitis. The subsequent course of ulcerative colitis in 25 children admitted to hospital during the period 1931 to 1971 is reviewed. The period of observation averaged 24 years, ranging from 1 to 41 years. 19 patients showed extracolonic manifestations. 4 patients ha...

A novel mutation at codon 441 in exon 10 of the adenomatous polyposis coli (APC) gene was identified in a South African family of mixed ancestry, using a convenient, non-radioactive, heteroduplex-SSCP screening assay. This single thymidine deletion after nucleotide position 1322 creates a frameshift resulting in a downstream stop codon at amino acid residue 453 of the APC gene. Genotypes of nin...