One of the main problems modern medicine is cancer, which second leading cause death after cardiovascular disease. Malignant neoplasms have been known for a long time; however, their study still presents significant difficulties. Modeling malignant processes in animals allow researchers to tumors and patterns growth characteristic humans. The process metastasis formation, remains be understood de...

Experimental determination of solubility and ternary phase diagram of chiral compound are of tedious and time consuming tasks, and in many cases, there is not enough experimental data for different enantiomeric compositions to access the experimental ternary phase diagram. Using thermodynamic models with predictive capability, having less dependency on experimental data, affords a great advanta...

Objective: The present study aimed at investigating the effectiveness of video modeling on social skills of children with Autism Spectrum Disorder (ASD). Methods: The current experimental study with pre-test, post-test design and control group was conducted on 24 male children with ASD aged 6-8 years from two special schools. The samples were selected by random sampling method and randomly div...

objective(s): osteoarthritis (oa), as a known degenerative joint disease, is the most common form of arthritis. in this study, we aimed to elucidate unclear pathogenesis of oa. materials and methods: rabbit models of oa were established by the transection of the anterior cruciate ligament. rabbits were randomly divided into three equal groups: the experimental group (oa modeling, treated with e...

The complexity of proteomes makes good experimental design essential for their successful investigation. Here, we describe how proteomics experiments can be modeled and how computer simulations of these models can be used to improve experimental designs.