Escherichia coli DNA polymerase I (pol I), discovered by Arthur Kornberg and colleagues in 1956. Thirteen years later, Paula de Lucia and John Cairns, at Stony Brook, New York, isolated an E. coli mutant, polA (its designation being a play on de Lucia’s first name, as proposed to Cairns by Julian Gross) that seemed to have less than 1% of the normal pol I activity. From this strain, a new DNA-p...