background: hyperbilirubinemia, or jaundice, is a life threatening disorder in newborns. it is a multifactorial disorder with many symptoms. generally, the physiological jaundice is the most prevalent type however in some regions pathological jaundice is also common. this review article focuses on a brief introduction to jaundice, its types and causes, measuring the bilirubin level, clinical ap...

background: malaria is the most important transfusion-transmitted infection (tti) in worldwide after viral hepatitis and human immunodeficiency virus (hiv) infection. the main objective of the present study was to review and evaluate the transmission of malaria via blood transfusion in iran. methods : a literature search was done without time limitation in the electronic databases as follows: p...

background: reservation of blood leads to blood wastage if the blood is not transfused. therefore, in some centers only blood type and screen are evaluated. in this study, the efficacy of a blood crossmatch-to-transfusion ratio was measured and then compared with the standard levels. methods: this prospective study was conducted during one year in a university hospital. during this period, 398 ...

transfusion of blood products from an infected person with aids, is meant to infect recipient. blood products such as whole blood, red blood cells, platelets, plasma, frozen blood precipitate, factor viii, factor ix, can be infected with hiv. transmissions from blood factors can be seen in plasma from thousands of donors that were collected in a container and were used to treat hemophilia. bloo...

the overall incidence of glucose-6-phosphate dehydrogenase (g6pd) deficiency in iranian population is estimated around 10%-14.9% . g6pd deficiency is an x-linked disorder and 80% of donors are usually male. at present, donors’ blood is not routinely screened for g6pd deficiency in iran blood bank where for detecting such enzyme deficiency, reliance is placed on pre-donation data. thus, the g6pd...

Background: Due to multiple roles of albumin in the body, injection of its medicinal product as one of the therapeutic or management strategies under conditions such as severe bleeding, burns, liver failure, and neonatal hemolytic diseases is on the physicians' agenda. Considering that albumin is the most abundant plasma protein, designing an appropriate method to purify it is highly important....

BACKGROUND Surgery in patients with sickle cell disease is associated with high morbidity. To reduce this high morbidity, different preoperative transfusion regimens were introduced. However, blood transfusion is associated with problems. This prospective study aims to establish the safety of conducting laparoscopic cholecystectomy without transfusion in sickle cell disease patients. METHODS...

INTRODUCTION Homozygous sickle cell carriers have an increased perioperative mortality. Some indications may justify an exchange blood transfusion to reduce the proportion of haemoglobin S. The advantages of general blood transfusion in a perioperative setting have not been proven and thus remain controversial. It is not clear whether reducing the proportion of haemoglobin S minimizes periopera...

An 11-month-old patient with idiopathic cardiomyopathy was scheduled for orthotopic heart transplantation. A perioperative exchange transfusion was performed because of elevated panel reactive antibody levels. This process was accomplished in the operating room prior to instituting cardiopulmonary bypass using a modified cardiopulmonary bypass circuit. In preparation for the procedure, the card...