Purpose: Spatially Fractionated Radiation Therapy (SFRT) is characterized by large differences in peak and valley doses. Preclinical clinical studies suggest that biological mechanisms lead to differential normal tissue tumor response compared uniform irradiation. We hypothesize evaluate effectiveness understand fundamental mechanisms, radiobiological rather than physical dose quantities should...

In this paper, we present our perspective on Model-Based User Interfaces (hereafter MBUI) paradigm and provide with our experience in this area combining high-level knowledge-based data models (i.e. ontologies) and reverse engineering processes to carry through a pragmatic MBUI vision. Our approach is based on using End-User Development (hereafter EUD) techniques (i.e. Programming by Example) t...

Ubiquitous computing is now mature enough to unleash the potential of Smart Homes. The obstacle is no more about hardware concerns but lies in how inhabitants can build, configure and control their Smart Home. In this paper, we defend the idea that End-User-Development (EUD), which considers inhabitants as makers rather than mere consumers, is an effective approach for tackling this obstacle. W...

Our contribution will review, analyze, discuss, and synthesize the research work done over the last 10 years exploring meta-design as a major framework for EUD. The overriding perspective of our approach is grounded in the basic assumption that the real impact of EUD transcends the developments to create new technologies but transform cultures by empowering all people to become active contribut...

Communities present considerable challenges for the design and application of supportive information technology (IT), especially when these develop in loosely-integrated, informal and scarcely organized contexts, like it is often the case of Communities of Practice (CoP). An approach that actively supports user communities in the process of IT appropriation can help alleviate the impossibility ...

In a world that is not predictable, improvisation, evolution, and innovation are more than luxuries: they are necessities. The challenge of design is not a matter of getting rid of the emergent, but rather of including it and making it an opportunity for more creative and more adequate solutions to problems. End-user development (EUD) provides the enabling conditions for putting owners of probl...

In recent years, Artificial Intelligence has become more and relevant in our society. Creating AI systems is almost always the prerogative of IT experts. However, users may need to create intelligent solutions tailored their specific needs. this way, can be enhanced if new approaches are devised allow non-technical directly involved definition personalization technologies. End-User Development ...

End-user development (EUD) activities where the end-user assumes a central role in creating or modifying software artefacts have the potential to offer meaningful experiential learning opportunities for students in IS courses. By providing hands-on exposure to technology platforms in the context of business problems and requirements, EUD activities can help bridge the gap between education and ...

Advances in the fields of IMRT and functional imaging have greatly increased the prospect of escalating the dose to highly active or hypoxic tumour sub-volumes and steering the dose away from highly functional critical structure regions. However, current clinical treatment planning and evaluation tools assume homogeneous activity/function status in the tumour/critical structures. A method was d...

In this work, we present how domain modeling and Programming by Example techniques can be combined to carry through a EUD approach. Our techniques are based on detecting iteration patterns from user monitoring as well as extracting knowledge about the user interface itself. Combining those, dynamic behavior can be characterized, getting maximum amount of semantic at each user step. This approac...