نتایج جستجو برای: estrogen receptor depen dent cancer
تعداد نتایج: 1449965 فیلتر نتایج به سال:
background: malignant neoplastic lesions of the breast are one of the main causes of cancer death among women. several factors can be influential in the treatment process of breast cancer patients. the expression status of estrogen and progesterone receptors in tumor cells is among the most important determinants affecting the treatment approach and prognosis of these patients. in this paper, w...
Estrogen-responsive endometrial cancer (EC) is prevalent in uterine cancer. Its precise molecular mechanisms remain to be elucidated partly because of limited availability estrogen-sensitive EC models recapitulating clinical pathophysiology. We previously established patient-derived cell (EC-PDC) spheroid culture with high expression estrogen receptor α (ERα). Using this EC-PDC, we study the tr...
Research has shown that obesity increases the risk for type 2 diabetes mellitus (Type DM) by promoting insulin resistance, serum estrogen levels upregulation of aromatase, and promotes release reactive oxygen species (ROS) macrophages. Increased circulating glucose been to activate mammalian target rapamycin (mTOR), a significant signaling pathway in breast cancer pathogenesis. Estrogen plays a...
background: systematic treatments such as hormone and chemotherapy are selected according to tumor characteristic after major therapeutic approaches such as surgery. this study attempted to analyze and compare the status of estrogen receptor (er) and progesterone receptor (pr) in primary and recurrent sites of breast cancer in patients. methods: we reviewed all medical records of breast cancer ...
Abstract Emerging studies show that testis-enriched genes play critical roles in several biological processes. The expression of these is tightly regulated and limited to immune-privileged organs; however, many them escape regulation are aberrantly expressed diseases such as cancer. Intriguingly, our genomic analysis revealed transcribed from previously considered gene deserts. We also found a ...
The cover image is based on the Research Article Neoadjuvant endocrine therapy expands stromal populations that predict poor prognosis in estrogen receptor-positive breast cancer by Heather M. Brechbuhl et al., https://doi.org/10.1002/mc.23377.
10503 Background: Genetic factors that contribute to endogenous estrogen synthesis and postmenopausal breast cancer risk are unknown. We set out test the hypothesis homozygous inheritance of common 1245A→C missense-encoding polymorphism in HSD3B1, which is (8-10%) White populations, functionally adrenal permissive increases aromatase substrate, androstenedione, associated with receptor-positive...
Robust H output feedback control problem for a class of switched linear discrete-time systems possessing normbounded uncertainty and time-varying delay is investigated. A switched dynamic output feedback controller is sought that can robust exponentially stabilize and reduce to a prescribed level the effect of disturbance input on the controlled output in the closed loop. A delay depen dent lin...
We evaluated the cytotoxicity of 1-dodecyl-3-methylimidazo-lium bromide ([C12mim][Br]) on HepG2 cells and its influence on plasma membrane permeability. The results showed that [C12mim][Br] inhibited HepG2 cell growth and decreased cell viability in a concentration-depen-dent manner. The results also revealed that [C12mim][Br] exposure induced apoptosis in [C12mim][Br]-treated HepG2 cells. In a...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید