نتایج جستجو برای: estrogen receptor depen dent cancer

تعداد نتایج: 1449965  

Journal: :middle east journal of cancer 0
sedigheh tahmasebi department of surgery, shiraz university of medical sciences, shiraz, iran behnam dalfardi student research committee, shiraz university of medical sciences, shiraz, iran abdolrasoul talei department of surgery, shiraz university of medical sciences, shiraz, iran akbar safaei department of pathology, shiraz university of medical sciences, shiraz, iran ahmad monabati department of pathology, shiraz university of medical sciences, shiraz, iran majid akrami department of surgery, shiraz university of medical sciences, shiraz, iran

background: malignant neoplastic lesions of the breast are one of the main causes of cancer death among women. several factors can be influential in the treatment process of breast cancer patients. the expression status of estrogen and progesterone receptors in tumor cells is among the most important determinants affecting the treatment approach and prognosis of these patients. in this paper, w...

Journal: :Biochemical and Biophysical Research Communications 2021

Estrogen-responsive endometrial cancer (EC) is prevalent in uterine cancer. Its precise molecular mechanisms remain to be elucidated partly because of limited availability estrogen-sensitive EC models recapitulating clinical pathophysiology. We previously established patient-derived cell (EC-PDC) spheroid culture with high expression estrogen receptor α (ERα). Using this EC-PDC, we study the tr...

Journal: :Cells 2023

Research has shown that obesity increases the risk for type 2 diabetes mellitus (Type DM) by promoting insulin resistance, serum estrogen levels upregulation of aromatase, and promotes release reactive oxygen species (ROS) macrophages. Increased circulating glucose been to activate mammalian target rapamycin (mTOR), a significant signaling pathway in breast cancer pathogenesis. Estrogen plays a...

Journal: :iranian journal of cancer prevention 0
hamid saeedi saedi dept. of radiation oncology, cancer research center, gilan university of medical sciences, rasht, iran mohammad-reza ghavam nasiri dept. of radiation oncology, cancer research center , mashhad university of medical sciences, mashhad, iran soodabeh shahidsales dept. of radiation oncology, cancer research center , mashhad university of medical sciences, mashhad, iran ali taghizadeh dept. of radiation oncology, cancer research center , mashhad university of medical sciences, mashhad, iran nama mohammadian dept. of radiation oncology, cancer research center , mashhad university of medical sciences, mashhad, iran

background: systematic treatments such as hormone and chemotherapy are selected according to tumor characteristic after major therapeutic approaches such as surgery. this study attempted to analyze and compare the status of estrogen receptor (er) and progesterone receptor (pr) in primary and recurrent sites of breast cancer in patients. methods: we reviewed all medical records of breast cancer ...

Journal: :Journal of the Endocrine Society 2022

Abstract Emerging studies show that testis-enriched genes play critical roles in several biological processes. The expression of these is tightly regulated and limited to immune-privileged organs; however, many them escape regulation are aberrantly expressed diseases such as cancer. Intriguingly, our genomic analysis revealed transcribed from previously considered gene deserts. We also found a ...

Journal: :Molecular Carcinogenesis 2022

The cover image is based on the Research Article Neoadjuvant endocrine therapy expands stromal populations that predict poor prognosis in estrogen receptor-positive breast cancer by Heather M. Brechbuhl et al., https://doi.org/10.1002/mc.23377.

Journal: :Journal of Clinical Oncology 2021

10503 Background: Genetic factors that contribute to endogenous estrogen synthesis and postmenopausal breast cancer risk are unknown. We set out test the hypothesis homozygous inheritance of common 1245A→C missense-encoding polymorphism in HSD3B1, which is (8-10%) White populations, functionally adrenal permissive increases aromatase substrate, androstenedione, associated with receptor-positive...

2011
Zhengui Song Georgi M. Dimirovski Jun Zhao

Robust H output feedback control problem for a class of switched linear discrete-time systems possessing normbounded uncertainty and time-varying delay is investigated. A switched dynamic output feedback controller is sought that can robust exponentially stabilize and reduce to a prescribed level the effect of disturbance input on the controlled output in the closed loop. A delay depen dent lin...

Journal: :Genetics and molecular research : GMR 2015
T H Li C Q Jing K L Gao W Y Yue S F Li

We evaluated the cytotoxicity of 1-dodecyl-3-methylimidazo-lium bromide ([C12mim][Br]) on HepG2 cells and its influence on plasma membrane permeability. The results showed that [C12mim][Br] inhibited HepG2 cell growth and decreased cell viability in a concentration-depen-dent manner. The results also revealed that [C12mim][Br] exposure induced apoptosis in [C12mim][Br]-treated HepG2 cells. In a...

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