BACKGROUND Cadmium (Cd), lead (Pb) and arsenic (As) are common environmental contaminants that have been associated with lower birthweight. Although some essential metals may mitigate exposure, data are inconsistent. This study sought to evaluate the relationship between toxic metals, nutrient combinations and birthweight among 275 mother-child pairs. METHODS Non-essential metals, Cd, Pb, As,...

ticular concern are “heavy metals,” which occur naturally in the earth’s crust and are defined in physiochemical terms as metals with a density at least 5 times as great as water. This definition translates into an approximate heavy-metal minimum density of 5, and—in addition to cadmium, lead, and mercury—the metals zinc, copper, iron, cobalt, nickel, tin, manganese, and molybdenum also qualify...

Metals are essential for the normal functioning of living organisms. Their uses in biological systems are varied, but are frequently associated with sites of critical protein function, such as zinc finger motifs and electron or oxygen carriers. These functions only require essential metals in minute amounts, hence they are termed trace metals. Other metals are, however, less beneficial, owing t...

Soil pollution with heavy metals draws a serious concern because of their detrimental effects on the living biota. The persistent and non-biodegradable nature of heavy metals eases their accumulation in the environment. Agricultural soils are receiving tremendous amount of pollutants from the various sources. During the last few decades, rapid urbanization, industrialization, injudicious and fa...

A variety of pathologies are associated with exposure to supraphysiological concentrations of essential metals and to non-essential metals and metalloids. The molecular mechanisms linking metal exposure to human pathologies have not been clearly defined. To address these gaps in our understanding of the molecular biology of transition metals, the genomic effects of exposure to Group IB (copper,...

Heavy metals accumulated by aquatic crustaceans in environmental studies are normally investigated using the whole body burden, with little regard paid to uptake in different tissues, to potential gender of life stage differences, or to the influence of nutrition on the test organism. This is likely to give erroneous conclusions for a dose-response relationship within the toxicity test and pote...

Microalgae are aquatic organisms possessing molecular mechanisms that allow them to discriminate non-essential heavy metals from those essential ones for their growth. The different detoxification processes executed by algae are reviewed with special emphasis on those involving the peptides metallothioneins, mainly the post transcriptionally synthesized class III metallothioneins or phytochelat...

Environmental pollution has increased many folds in recent years and in some places has reached levels that are toxic to living things. Among pollutant types, toxic heavy metals and metalloids are among the chemicals that pose the highest threat to biological systems (Jjemba 2004). Unlike organic pollutants, which are biodegradable, heavy metals are not degraded into less hazardous end products...

Concentrations of both essential (Zn and Cu) and non essential (As, Cd, Pb, Hg, Ni) metals were measured in the organs (mantle, branchial hearts, gill and digestive gland) of Sepia pharaoniscaptured in coastal water of Bushehr Province on thePersian Gulf (Iran). The relationships between S. pharaonis size (mantle length) and metals concentrations in tissues were investigated by linear regressio...