It is not known if the ruminant animal gastrointestinal tract (GIT) can oxidise essential amino acids (AA) other than leucine. Therefore, the oxidation of four essential AA (leucine, lysine, methionine and phenylalanine), supplied systemically as labelled 1-13C forms, was monitored across the mesenteric-drained viscera (MDV; small intestine) and portal-drained viscera (PDV; total GIT), as part ...

We read with interest the work by Jeppesen et al (1) examining the fatty acid content of plasma phospholipids in patients with malabsorption and patients receiving home parenteral nutrition (HPN). In that article, patients with fat malabsorption were subgrouped according to the severity of malabsorption (fat malabsorption ≤50% and fat malabsorption >50%), whereas patients receiving HPN were gro...

Four ewes, each fitted with a rumen cannula and with catheters in the mesenteric artery and portal and mesenteric veins, received continuous intrarumen infusions of water or of short-chain fatty acids (SCFA). SCFA infusions were isoenergetic (83 kJ/h) and provided rumen molar proportions (acetate:propionate:butyrate) of 70:20:10, 50:40:10 or 50:20:30. The rumen SCFA production rate with the bas...

How effective are twelve step programs? Although AA has been around for more than 75 years, the real answer to this question is that no one knows. Studies which have compared AA with a control group have shown mixed results. This article reviews the essential studies of the effectiveness of AA and concludes that while some people find that AA is a useful aid to abstinence, others find AA to be ...

Milk contains free amino acids (AAs) that play essential roles in maintaining the growth and health of infants, and D-AA isomers are increasingly being recognized as important signalling molecules. However, there are no studies of the different characteristics of chiral AA (C-AA) from different milk origins. Here, UPLC coupled to ion-mobility high-resolution MS (IM-HRMS) was employed to charact...