in this paper, two patients with severe dysphagia and esophageal stricture secondary to epidermolysis bullosa are presented and discussed. they are siblings of an affected family. primary resection and anastomosis had been performed previously in both patients, but dysphagia had recurred. we treated these patients with free jejunal graft to the esophagus with excellent results. both patients ar...

a 69-year-old woman was admitted to hospital 4 times from november 2007 to june 2009. the patient had silicosis complicated by broncholithiasis, esophagobronchial fistula, and relapsed tuberculosis. she had worked as a stone crusher for 3 years and was exposed to a large amount of quartz dust. barium esophagography, gastroesophageal endoscopy, and biopsy suggested esophageal-related chronic inf...

the patient is a 69 years old female presented with chest pain and rapidly progressive dysphagia. then she suffered of hematemesis and aphagia. in evaluation of patient, a intramural hematoma obstructing esophageal lumen was demonstrated which was accompanied with mucosal ulceration and bleeding. it appears that this complication occurred in the context of concomitant use of alendronate with as...

abstract intraabdominal schwannomas are rare tumors that may arise from viscera or abdominal wall. the rarity accompanied by occurrence in odds places may make their diagnosis difficult and delayed. we present a case of distal paraesophageal schwannoma with long-term cachexia. a34-year-old man presented with long-lasting vomiting, dysphagia, and progressive cachexia for four years. multiple par...

patients with syndrome x coronary disease represent a heterogeneous group of patients. medical treatment with dilators and calcium channel blockers are not very effective. we evaluated the use of transmyocardial laser revascularization (tmlr) in treating 5 patients with this syndrome. between may 2002 to december 2005, 5 patients with cardiac syndrome x (mean age of 49.7 years) underwent tmlr. ...

managed in the primary care setting. Surveys suggest that approximately 20 percent of U.S. adults have symptoms of GERD at least once a week.4 A subgroup of patients with GERD develop severe complications that include erosive esophagitis, stricture formation, Barrett’s esophagus, and adenocarcinoma of the esophagus. Because Barrett’s esophagus is thought to be associated with the development of...

The increasing incidence of esophageal adenocarcinoma (EAC) is mirrored by the increasing prevalence of Barrett esophagus, a precursor lesion resulting in a large number of individuals "at risk" for this lethal malignancy. Among patients with Barrett esophagus, only about 0.3% annually will develop EAC. Because large numbers of patients are followed in endoscopic surveillance, there is a need f...

The aim of this study was to determine the role of the superior laryngeal nerve (SLN) in the following esophageal reflexes: esophago-upper esophageal sphincter (UES) contractile reflex (EUCR), esophago-lower esophageal sphincter (LES) relaxation reflex (ELIR), secondary peristalsis, pharyngeal swallowing, and belch. Cats (N = 43) were decerebrated and instrumented to record EMG of the cricophar...

Aim. To determine the diagnostic value of endosonography in primary and secondary esophageal tumors.
 Materials methods. Between 2018 2022, 118 patients with changes were managed at Blokhin National Medical Research Center for Oncology. Primary imply invasion esophagus directly by a tumor, mean wall tumor from outside, transition stomach to esophagus.
 Results. All had esophagogastrod...

BACKGROUND Esophageal adenocarcinoma develops through a multistage process which is characterized histopathologically by progression from Barrett's intestinal metaplasia to Barrett's esophagus with dysplasia and ultimately to adenocarcinoma. The genetic basis of this process is increasingly well understood, but no studies have examined the role of the transcription factor c-myb in this disease....