epstein-barr virus (ebv) was discovered 50 years ago from an african burkitt lymphoma cell line. ebv-associated lymphoproliferative disorders (lpds) are life-threatening diseases, especially in children. in this article, we review ebv-associated lpds, especially in the area of primary immunodeficiency disease (pid). we searched pubmed for publications with key words including ebv infection, lym...

background: the aim of this study was to determine the prevalence and viral load of epstein–barr virus (ebv) and human herpesvirus‑6 (hhv‑6) in different histopathologic grades of oral squamous cell carcinoma (oscc). methods: forty‑five formalin‑fixed paraffin‑embedded tissue section of oscc patients were analyzed by quantitative real‑time polymerase chain reaction for detection of ebv and hhv‑...

background: among the eight known human herpes viruses, epstein- barr virus (ebv) is considered to be sexually transmissible. this study was conducted to evaluate the seroepidemiology of this infection in married and unmarried iranian couples. methods: in this comparative observational and cross-sectional study, 160 men and women were divided into married and unmarried groups. serum igg and igm...

opportunistic infections are the leading cause of hospitalization and morbidity in human immunodeficiency virus (hiv) positive patients and are the most common cause of death between them. we aimed to measure igg antibody against ebv viral capsid antigen (ebv-vca igg) to determine the seroprevalence of this infection in hiv-positive population. a case-control study between september 2011 and oc...

introduction: quantification of epstein - barr virus (ebv) in peripheral blood mononuclear cells (pbmnc) of allogenic bone marrow transplant (bmt) recipients is important because ebv-associated posttransplant lymphoproliferative disease (ptld) can occur after transplantation due to immunosup-pression therapy. methods: to this end we chose real-time pcr using taqman probe. for the standard curve...

conclusions considering the results, accurate and on time diagnosis of ebv primary infection in both children and adolescents will help prevent unnecessary hospitalization, medication and incorrect medical decisions. in addition, this will decrease further treatment costs and related medical procedures. background many children become infected with epstein-barr virus (ebv) during their childhoo...

An unknown environmental agent has been suspected to induce systemic lupus erythematosus (lupus) in man. Prompted by our recent immunochemical findings, we sought evidence for an association between Epstein-Barr virus infection and lupus. Because the vast majority of adults have been infected with Epstein-Barr virus, we chose to study children and young adults. Virtually all (116 of 117, or 99%...

OBJECTIVE Epstein-Barr virus-positive diffuse large B-cell lymphoma is a provisional entity in the 2008 World Health Organization classification of tumors of hematopoietic and lymphoid tissues. Reports on the characteristics and clinical outcome of this disease in different geographic regions showed great disparities. METHODS To define the clinical characteristics as well as the prognostic im...

Marmoset blood leukocytes transformed in vitro by Epstein-Barr virus regularly release extracellular infectious Epstein-Barr virus with high titers of transforming activity. By comparison, human umbilical cord leukocytes and adult human leukocytes transformed by Epstein-Barr virus release either no extracellular infectious virus or small amounts, irregularly.

This prospective study was carried in Mahila Chikitsalya and State Zenana Hospital attached to S.M.S. Medical College, Jaipur, between October 1992 to March 1993. Live born male babies delivered during this period were examined for the presence of epstein pearls on the prepuce. Prepucial epstein pearl was cleaned with cotton swab to remove any smegma, which might mimic epstein pearl. Then its s...