Catecholamine drugs are aromatic vic-diols in which both the 3or 4-position is unsubstituted and these positions are not sterically blocked. Epinephrine(EP) or adrenaline(I) and norepinephrine(NE) or noradrenaline (II) are catecholamine drugs that are widely used in the treatment of allergic emergencies, status asthmatics, bronchial asthma, ventricular bradycardia, cardiac arrest, glaucoma, and...

BACKGROUND Enterovirus 71 (EV71) infections may be associated with neurological complications, including brainstem encephalitis (BE). Severe EV71 BE may be complicated with autonomic nervous system (ANS) dysregulation and/or pulmonary edema (PE). ANS dysregulation is related to the overactivation of the sympathetic nervous system, which results from catecholamine release. OBJECTIVE The aims o...

■ ■ 2.5 μm particle size provides the flexibility to operate on a variety of systems IN T RO DU C T IO N Hydrophilic-interaction chromatography (HILIC) is increasingly becoming a method of choice for the analysis of polar compounds [1-5]. One set of polar analytes that poses particular challenges are the monoamine neurotransmitters, dopamine (DA), serotonin (5-HT), epinephrine (EP), and norepin...

A dimeric Cu(II) complex [Cu(μ(2)-hep)(hep-H)](2)·2ClO(4) (1) containing bidentate (hep-H=2-(2-hydroxyethyl)pyridine) ligand was synthesized and characterized by single crystal X-ray diffraction studies. Each Cu-ion in 1 is in a distorted square pyramidal geometry. Further 1 along with silver nanoparticles (SNPs) have been used as modifier in the construction of a biomimetic sensor (1-SNP-GCPE)...

The title compound, C(11)H(16)O(7), was obtained from the breakage reaction of the glycosidic bond of 5'-de-oxy-2',3'-diacetyl-inosine. The ribofuran-ose ring has a C2-exo, C3-endo twist configuration. No alteration of the relative configuration compared with d-(-)-ribose is observed.

iontophoresis of epinephrine for assessment of neuromuscular junction response is a new technique that can improve diagnose of neuromuscular dysfunction. the purpose of this study was to investigate the effects of iontophoresis of epinephrine on neuromuscular junction response. iontophoresis of epinephrine solution (1mg/ml), sodium chloride, calcium gluconate, epinephrine with sodium chloride a...

The effect of epinephrine on phosphatidate phosphohydrolase (PAP) activity of isolated human hepatocytes was studied. Epineprine inhibited the enzyme activity progressively at concentrations above 0.1 µM, reaching a maximum inhibition of 64.5% at 100 µM concentration. Inclusion of alprenolol, a β-receptor blocker, in the incubation mixture abolished the inhibitory effect of epinephrine on P...

We present a theoretical and numerical investigation of the effect of a timevarying external driving force on interface growth. First, we derive a relation between the roughening exponents which comes from a generalized Galilean invariance, showing how the critical dimension of the model is tunable with the external field. We further conjecture results for the exponents in two dimensions, and f...

The dependence of the fractal behaviors of the pomeron induced system in deep inelastic lepton-nucleon scattering upon the diffractive kinematic variables is found not to sensitive to the distinct parameterization of the pomeron flux factor and the structure function. A feasible experimental test of the phenomenological pomeron model in DESY ep collider HERA is proposed.

Introduction: Several researches have reported that stress is able to inhibit the development of morphine tolerance via activating of Hypothalamic-Pituitary-Adrenal (HPA) axis. In the present study we tried to examine the effect of epinephrine, the product of adrenal medulla, on the development of morphine tolerance. Methods: Analgesic tolerance was induced by intrathecal (i.t.) injection of...