background: cirrhotic patients are at a greater risk of different kinds of arrhythmias. despite the well-known arrhythmogenic effects of halothane, developing countries continue to use halothane due to its low cost. this study was designed to investigate the pathophysiology of halothane untoward effects on heart rhythm moreover was aimed to explore the effect of halothane anesthesia on the thre...

the use of local anesthesia with lidocaine containing epinephrine in patients with cardiac disease is controversial in the literature. the aim of our study was determining the safety of use the local anesthesia contain epinephrine in patients with ischemic heart disease that undergoing reconstructive surgery. thirty two patients that had known ischemic heart disease and candidate to undergo rec...

The effects of alpha and beta-adrenergic stimulation on triacylglycerol secretion were investigated in isolated rat hepatocytes. Epinephrine within 3h of incubation suppressed triacylglycerol secretion by 35% and increased its cellular content by 18%. The inhibitory effect of epinephrine was abolished by inclusion of phentolamine and also prazosin but not with propranolol. Trifluoperazine c...

Introduction: Epinephrine-containing lidocaine is the most used anestheic drug in dentistry. The aim of this study was to investigate the hemodynamic changes following local infiltration of 2%lidocaine with 1:80,000 epinephrine in subjects undergoing orthognatic surgery under general anesthesia. Methods: Twenty five patients without any systemic disease participated. After general anesthesia, t...

complex mechanisms have been known for keeping blood pressure in normal level. in fact, these mechanisms have inter-related functions and can be dysregulated by both internal and external stimuli while cardiovascular system functions to minimize these changes. vasoconstrictors can cause clinical and hemodynamical changes as 1-2 cartridges of epinephrine containing lidocaine can has no considera...

phylaxis, inhaled epinephrine from a metered-dose inhaler is sometimes recommended as a simple and easily administered alternative to injectable epinephrine. This study evaluated the practicality of inhaled epinephrine in a pediatric population at risk for anaphylaxis by evaluating the rate and extent of epinephrine absorption after inhalation. Study Population. A total of 19 children ages 6 to...

BACKGROUND Epinephrine administered by low umbilical venous catheter (UVC) or endotracheal tube (ETT) is indicated in neonates who fail to respond to positive pressure ventilation and chest compressions at birth. Pharmacokinetics of ETT epinephrine via fluid-filled lungs or UVC epinephrine in the presence of fetal shunts is unknown. We hypothesized that epinephrine administered by ETT or low UV...

Abstract This study aimed to assess the effect of inferior alveolar nerve (IAN) block mandible and infiltration anesthesia maxilla using lidocaine plus epinephrine or prilocaine with felypressin anesthetic agents on systolic diastolic blood pressures, heart rate (HR) peripheral oxygen saturation patients. randomized double-blind clinical trial evaluated 112 patients in four groups (n=28) based ...