Although treated properly for epilepsy, a number of epileptic children have intractable seizures and about 5-10 per cent of them do not respond to anti -epileptic drugs. In the years 1986-1996 about 10,000 epileptic patients were treated in the Children's Medical Center in Tehran. A retrospective study of their medical records revealed that 41 of them had intractable seizures. I Of these 4...

how to cite this article: hashemiaghdam a, sharifi a, miri m, tafakhori a. seizure-control effect of levatiracetam on juvenile myoclonic epilepsy and other epileptic syndromes: literature review of recent studies. iran j child neurol. spring 2015;9(2):1-8. abstract objective various epileptic syndromes may present in adolescence and juvenile myoclonic epilepsy (jme) is known to be the most comm...

UNLABELLED A study of concentrated attention patterns in epileptic patients was conducted with the objectives: characterization of the patients' epileptic condition; assessment of the concentrated attention levels in epileptic and nonepileptic individuals; comparison of the attention levels of the two groups. An evaluation was performed of 50 adult outpatients with complex partial seizures and ...

PURPOSE To investigate the association between genotype (methyl-CpG-binding protein 2 (MECP2 gene mutation)) and epileptic seizure phenotype in Rett syndrome. METHODS We used the British Isles Rett syndrome survey to identify 137 subjects with one of the nine most frequent MECP2 gene mutations and invited their parents or carers to participate in a postal questionnaire and telephone interview...

Investigators from the University Leipzig and University of Tübingen report mutations of KCNA2 as a novel cause of epileptic encephalopathy.

Psychogenic non-epileptic seizures (PNES) need to be differentiated from epileptic seizures as the management varies for both. Presence of tongue biting, falling and urinary incontinence favors a diagnosis of epileptic seizures. We report two children with features suggestive of epileptic seizures that were eventually diagnosed as PNES with the help of video-EEG monitoring.

PURPOSE We aimed to define the characteristics of epileptic nystagmus and correlate those with other clinical findings in a large number of patients. METHODS We report a patient with epileptic nystagmus and additionally reviewed the reported clinical features of 36 more patients through a systematic literature search. We analyzed the characteristics of epileptic nystagmus and attempted correl...

Valproic acid is widely used as an anti-epileptic globally. Anti-epileptic action is mediated by Gamma Amino Butyric Acid (GABA) receptors. In past and recently, several other clinical outcomes have been proposed by various studies. These under-reported clinical actions apart from anti-epileptic activity are mediated by various intracellular and extracellular pathways. Several mechanisms like H...