Oxidative stress has been suggested as a consequence and as a cause of epileptic seizures. Researches indicate Achillea wilhelmsii (A.wilhelmsii) has anti-oxidant and anti-spasmic effects on central nervous system. This plant grows in most part of Iran. An Iranian research that done in 2013 showed that the hydroalcoholic extract of Achillea wilhelmsii possesses an antioxidant effect in the brai...

PURPOSE We aimed to investigate the effects of levetiracetam on oxidative stress which is one of the new antiepileptic drugs in epileptic patients. METHODS The study consisted of 21 patients with cryptogenic partial epilepsy. We determined the urinary 15F-2t-isoprostane levels of the 30 patients which is a marker of oxidative stress. Morning urine samples were collected from the patients befo...

BACKGROUND There is an increasing attention towards the relationship between oxidative stress and epilepsy. The effect of antiepileptic drugs on oxidant status is of major interest. Antiepileptic drugs can increase levels of free radicals, which consequently might lead to seizures. Carbamazepine (CBZ) is an antiepileptic drug commonly used in childhood and adolescence. OBJECTIVES Therefore we...

BACKGROUND Epileptic seizures are often associated with changes in cardiac autonomic function. Yet atrial fibrillation (AFib) or atrial flutter (AFlu) following epileptic seizures has only rarely been reported in the past. OBJECTIVES To describe and characterize patients who experienced lone AFib or AFlu as a consequence of epileptic seizures. DESIGN Case reports. SETTING University teach...

To the Editor: Meditation is a widely adopted stress-relieving mental exercise associated with altered cognition and behavior. Recently, there has been debate [1,2] over the influence of meditation, and transcendental meditation (TM) in particular, on epilepsy. This debate was seemingly triggered by a view suggesting a potential epileptogenic influence of meditation [3], implying that long-term...

Aims: To assess and compare the body mass index (BMI), serum leptin, and lipid peroxidation represented by serum malondialdehyde (MDA) levels in epileptic patients on valproate (VPA) and topiramate (TPM) monotherapy for at least 6 months taking in consideration dosage and duration of therapy, in comparison to healthy controls. Methods: A cross-sectional, case-series study design was adopted, fo...

A 48-year-old male was diagnosed with both drug resistant epilepsy and psychogenic nonepileptic seizures. Both diagnoses were confirmed by video-EEG monitoring. His epileptic seizures were a consequence of right mesial temporal sclerosis. He was diagnosed by a psychiatrist to have depression and posttraumatic stress disorder (PTSD). Following a right anterior temporal resection he became seizur...