Inflammatory linear verrucous epidermal nevus is a variant of verrucous epidermal nevus, characterized by recurrent inflammatory phenomena. Despite well-established clinical manifestations, the differential diagnosis between inflammatory linear verrucous epidermal nevus and linear psoriasis remains difficult. Clinical history, physical examination and histopathology analysis may not be sufficie...

Corresponding author: Wei-Ming Wu, Department of Dermatology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Ta-Pei Road 123, Niao-Sung Hsiang, 83301 Kaohsiung, Taiwan TEL: 886-7-7317123 ext. 2299 FAX: 886-7-7337612 E-mail: [email protected] Funding source: none Confl ict of interest: none declared CASE REPORT A 24-year-old girl presented with linear verrucous skin lesions sinc...

Background: Epidermal nevus is a common skin hamartoma. Its definite treatment is difficult and in most cases the disease has recurrence. Objective: Evaluation of topical tretinoin 0.05% and 5 Fluorouracil (5FU) 5% in the treatment of epidermal nevus. Patients and Methods: Fifteen patients with epidermal nevus referred to skin clinic in Razi Hospital in Tehran whose diagnoses were confirm...

9.6 mg/dL, serum phosphate: 1.8mg/dL; alkaline phosphatase: 982 U/L. Acid load test was negative. TMP/GFR: 0.5, Magnetic resonance imaging of the brain showed interdigitation of gyri in the right frontal lobe. X-ray showed changes of rickets. Biopsy of the skin lesion was suggestive of epidermal nevus. He was started on phosphate mixture Sanklecha M, Singhal S, et al. Hereditory spherocytosis: ...

conservatively in neonatal intensive care unit. Abdominal distension decreased gradually. He passed stools on day 5 of admission. Repeat X-ray abdomen showed no air fluid levels. He was started on feeds gradually and discharged on day 18 of life. His serial USG abdomen showed gradual decrease in right adrenal hematoma with complete resolution by six weeks of age with no calcifications and norma...

Inflammatory linear verrucous epidermal nevus and linear psoriasis are sometimes hard to differentiate clinically and pathologically. Although immunohistochemical expression of keratin 10 (K10), K16, Ki-67, and involucrin may be useful for differentiating both entities, these results have been reported in only a few cases. We collected data from 8 patients with inflammatory linear verrucous epi...

We report phakomatosis pigmentovascularis (PPV) detected in a 40- year-old male characterized by the presence of a port-wine stain in the background of aberrant Mongolian spots covering the back, nevus of Ota, ocular melanosis, epidermal nevus and a scaly patch with the diagnosis of discoid lupus erytematosus. These associations have not been reported yet.

We report a case of epidermal nevus syndrome involving the brain in which there is chronic occlusion of the left distal internal carotid artery resulting in ipsilateral atrophy. Orbital and cerebellopontine angle cistern lipomas and a wide cortical developmental malformation are associated with the condition. We present MR imaging findings of a patient and discuss features in the context of oth...

Gorlin syndrome (also known as basal cell nevus syndrome) is a hereditary condition characterized by development of numerous epidermal and follicular tumors. Mutations in theSHH signaling pathway are key drivers this disease. It currently unknown whether SHH mutations non-epidermal types play role phenotypes, the tumor microenvironment, or altered skin development. Through lineage tracing using...

Papular epidermal nevus with "skyline" basal cell layer (PENS) is a very rare type of keratinocytic nevus and is associated with extracutaneous findings such as neurological symptoms in about 50% of the cases. Therefore, it is also referred to as PENS syndrome. Clinically visible hyperkeratotic papules and plaques already appear at birth or shortly thereafter, while neurological symptoms such a...