Following spinal cord injury, profound vascular changes lead to ischemia and hypoxia of spinal cord tissue. Since fibroblast growth factor 2 (FGF2) has angiogenic effects, its delivery to the injured spinal cord may attenuate the tissue damage associated with ischemia. To limit systemic mitogenic effects, FGF2 was delivered to the spinal cord via a gel of hyaluronan and methylcellulose (HAMC) i...

The uncertainty in hypocenters and origin times depends on measurement error (the wrong onset is picked) and error in the travel-time tables (and thus earth model) used. The errors in the tables comprise a baseline shift (the average difference over all stations is not zero) and the residuals about the baseline. The residuals are usually referred to as model error. Baseline error only affects o...

To examine the role of axonal ion deregulation in acute spinal cord injury (SCI), white matter strips from guinea pig spinal cord were incubated in vitro and were subjected to graded focal compression injury. At several postinjury times, spinal segments were removed from incubation and rapidly frozen. X-ray microanalysis was used to measure percent water and dry weight elemental concentrations ...

PURPOSE To study various standardized uptake value (SUV)-based approaches to ascertain the best strategy for delineating metabolic tumor volumes (MTV). METHODS AND MATERIALS Twenty-two consecutive previously treated esophageal cancer patients with positron emission tomography (PET) imaging and computed tomography (CT)-based radiotherapy plans were studied. At the level of the tumor epicenter,...

[1] The global ionospheric map (GIM) is used to observe variations in the total electron content (TEC) of the global positioning system (GPS) associated with 35 M 6.0 earthquakes that occurred in China during the 10-year period of 1 May 1998 to 30 April 2008. The statistical result indicates that the GPS TEC above the epicenter often pronouncedly decreases on day 3–5 before 17 M 6.3 earthquakes...

Although relatively little is known of the mechanisms involved in secondary axonal loss after spinal cord injury (SCI), recent data from in vitro models of white matter (WM) injury have implicated abnormal sodium influx as a key event. We hypothesized that blockade of sodium channels after SCI would reduce WM loss and long-term functional deficits. To test this hypothesis, a sufficient and safe...