نتایج جستجو برای: enhanced coagulation

تعداد نتایج: 392277  

Journal: :Critical Care 2003
Matthias Riewald Wolfram Ruf

Cellular signaling by proteases of the blood coagulation cascade through members of the protease-activated receptor (PAR) family can profoundly impact on the inflammatory balance in sepsis. The coagulation initiation reaction on tissue factor expressing cells signals through PAR1 and PAR2, leading to enhanced inflammation. The anticoagulant protein C pathway has potent anti-inflammatory effects...

Journal: :American journal of physiology. Heart and circulatory physiology 2015
Marlene E Starr Hitoshi Takahashi Daiki Okamura Brittany A Zwischenberger Amy A Mrazek Junji Ueda Arnold J Stromberg B Mark Evers Charles T Esmon Hiroshi Saito

Sepsis is a life-threatening clinical condition that is particularly serious among the elderly who experience considerably higher mortality rates compared with younger patients. Using a sterile endotoxemia model, we previously reported age-dependent mortality in conjunction with enhanced coagulation and insufficient levels of anti-coagulant factor activated protein C (aPC). The purpose of the p...

Journal: :international journal of hematology-oncology and stem cell research 0
mehrdad payandeh medical biology research center, kermanshah university of medical science, kermanshah, iran. hoshang yousefi blood transfusion research center, high institue for research and education in transfusion medicine,science, kermanshah, iran. mohammad erfan zare medical biology research center, kermanshah university of medical science, kermanshah, iran; student atefeh nasir kansestani medical biology research center, kermanshah university of medical science, kermanshah, iran; student zohreh rahimi medical biology research center, kermanshah university of medical science, kermanshah, iran; departm dariush pourmand department of medical lab science, paramedicine faculty, kermanshah university of medical science, kermanshah, iran

introduction: the main inhibitors of coagulation pathway are antithrombin (at), protein c and protein s. these inhibitors are necessary to prevent thromboembolism. hereditary deficiency of inhibitors is the main cause of alteration in balance between the anti-clotting and the formation of thrombin. patients with this abnormality are susceptible to venous thromboembolism (vte). two major clinica...

Journal: :iranian journal of pediatric hematology and oncology 0
رضا رباطی r robati department of microbiology, science and research branch, islamic azad university, fars, iranگروه میکروبیولوژی، دانشگاه آزاد اسلامی، واحد علوم و تحقیقات فارس،ایران محمد مهدی فرخی mmm farokhi department of microbiology, science and research branch, islamic azad university, fars, iranگروه میکروبیولوژی، دانشگاه آزاد اسلامی، واحد علوم و تحقیقات فارس،ایرانسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch)

background some of the dental procedures can cause bleeding. bleeding control can be difficult in some patients because of systemic disease or chronic anticoagulant therapy, so they may be at increased risk for bleeding occurrences or even death following invasive dental procedures. this study was schemed to measure the knowledge of general dentists in shiraz city regarding coagulation tests pe...

2016

Burn injury is traditionally referred to as a common triggering cause of acute coagulopathy, ranging from subclinical activation of coagulation to fulminant overt Disseminated Intravascular Coagulation (DIC). Coagulopathy associated with burn injury was well recognized as early as the 1970s.1,2 Coagulopathy in burn patients is considered to be driven by an endothelial injury, release of tissue ...

Journal: :International Journal of Molecular Sciences 2021

Obstructive sleep apnoea (OSA) is a common disease which characterised by repetitive collapse of the upper airways during resulting in chronic intermittent hypoxaemia and frequent microarousals, consequently leading to sympathetic overflow, enhanced oxidative stress, systemic inflammation, metabolic disturbances. OSA associated with increased risk for cardiovascular morbidity mortality, acceler...

2011
Paola Saracco Pasquale Vitale Carlo Scolfaro Berardino Pollio Mauro Pagliarino Fabio Timeus

Sepsis related coagulopathy ranges from mild laboratory alterations up to severe disseminated intravascular coagulation (DIC). There is evidence that DIC is involved in the pathogenesis of microvascular dysfunction contributing to organ failure. Additionally, the systemic activation of coagulation, by consuming platelets and coagulation factors, may cause bleeding. Thrombin generation via the t...

2001
J. Ma

Laboratory and full-scale experiments were conducted for enhancing the coagulation of stabilised surface waters with high organic content by permanganate preoxidation. It was indicated that permanganate preoxidation enhanced both the processes of coagulation and filtration of selected surface waters, River Songhua water, Qitaihe Reservoir water and Ba Reservoir water. Permanganate preoxidation ...

Journal: :Journal of medical virology 2002
Eric C M Van Gorp Tatty E Setiati Albert T A Mairuhu Catharina Suharti Hugo ten Cate Ht Wil M V Dolmans Jos W M Van Der Meer C Erik Hack Dees P M Brandjes

The mechanisms contributing to bleeding complications in dengue hemorrhagic fever were studied by investigating the pattern of activation of the coagulation and fibrinolytic systems in 50 children with severe dengue hemorrhagic fever. Thirteen patients (26%) died, and activation of coagulation was most pronounced in the deceased group. Fibrinolysis was also activated, but this activation was re...

Journal: :Blood 2009
Anetta Undas Konstanty Szułdrzyński Kathleen E Brummel-Ziedins Wiesława Tracz Krzysztof Zmudka Kenneth G Mann

We evaluated systemic alterations to the blood coagulation system that occur during a coronary thrombotic event. Peripheral blood coagulation in patients with acute coronary thrombosis was compared with that in people with stable coronary artery disease (CAD). Blood coagulation and platelet activation at the microvascular injury site were assessed using immunochemistry in 28 non-anticoagulated ...

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