نتایج جستجو برای: energy metabolites

تعداد نتایج: 722224  

2017
Gurudeeban Selvaraj Satyavani Kaliamurthi Zeynep Elibol Cakmak Turgay Cakmak

The present study aimed to evaluate the efficiency of microalgae metabolites as a ligand for anti-diabetic target proteins namely Glucokinase, Fructose-1, 6-bisphosphatase, Glycogen synthase kinase, Cytochrome P450, multi-drug resistant protein, and Peroxisome proliferators activated receptor-γ (PPARγ) using computational approach. Three-dimensional structure of microalgal metabolites retrieved...

Journal: :Journal of pharmaceutical and biomedical analysis 2010
Rune Isak Dupont Birkler Nicolaj Brejnholt Støttrup Sigurd Hermannson Torsten Toftegaard Nielsen Niels Gregersen Hans Erik Bøtker Mette Findal Andreasen Mogens Johannsen

Research within the field of metabolite profiling has already illuminated our understanding of a variety of physiological and pathological processes. Microdialysis has added further refinement to previous models and has allowed the testing of new hypotheses. In the present study, a new ultra-performance liquid chromatography/electrospray-tandem mass spectrometry (UPLC-ESI-MS/MS) method for the ...

2017
Teklab Gebregiworgis Chandirasegara Massilamany Arunakumar Gangaplara Sivasubramani Thulasingam Venkata Kolli Mark T. Werth Eric D. Dodds David Steffen Jay Reddy Robert Powers Chandirasegaran Massilamany

Journal: : 2022

The Effect of Different Energy Level on Blood Metabolites, Bacterial Population Small Intestine and Performance Arian Broiler Chickens

2015
Xiaoning Wang Guoxiang Xie Xiaoyan Wang Mingmei Zhou Huan Yu Yan Lin Guangli Du Guoan Luo Ping Liu

Zheng is the basic theory and essence of traditional Chinese medicine (TCM) in diagnosing diseases. However, there are no biological evidences to support TCM Zheng differentiation. In this study we elucidated the biological alteration of cirrhosis with TCM "Liver-Kidney Yin Deficiency (YX)" or "Dampness-Heat Internal Smoldering (SR)" Zheng and the potential of urine metabonomics in TCM Zheng di...

2017
Pengyi Zhang Xiangjing Meng Dongmei Li Richard Calderone Dewei Mao Bo Sui

Gut microbiota and their metabolites have been linked to a series of chronic diseases such as obesity and other metabolic dysfunctions. Obesity is an increasingly serious international health issue that may lead to a risk of insulin resistance and other metabolic diseases. The relationship between gut microbiota and the host is both interdependent and relatively independent. In this review, the...

2017
Jossias A. Duvane Tiago F. Jorge Ivete Maquia Natasha Ribeiro Ana I. F. Ribeiro-Barros Carla António

Miombo and Mopane are ecological and economic important woodlands from Africa, highly affected by a combination of climate change factors, and anthropogenic fires. Although most species of these ecosystems are fire tolerant, the mechanisms that lead to adaptive responses (metabolic reconfiguration) are unknown. In this context, the aim of this study was to characterize the primary metabolite co...

2014
W. M. Yin X. Xu Y. He G. B. Wei Y. H. Sima Xu Shi-Qing

The feasibility of using Bombyx mori as model animal is attracting more attention. Whether the effect of drugs on the metabolite profiling was consistent with those in mammals was an aspect to evaluate the feasibility of B. mori as model animal. In this study, we used acetaminophen to treat Dazao fifth-instar B. mori, and its metabolites in hemolymph were detected by gas chromatography-mass spe...

2013
Junji Okuda Shinnichiro Niizuma Tetsuo Shioi Takao Kato Yasutaka Inuzuka Tsuneaki Kawashima Yodo Tamaki Akira Kawamoto Yohei Tanada Yoshitaka Iwanaga Michiko Narazaki Tetsuya Matsuda Souichi Adachi Tomoyoshi Soga Genzou Takemura Hiroshi Kondoh Toru Kita Takeshi Kimura

BACKGROUND Heart failure is associated with changes in cardiac energy metabolism. Glucose metabolism in particular is thought to be important in the pathogenesis of heart failure. We examined the effects of persistent overexpression of phosphoglycerate mutase 2 (Pgam2), a glycolytic enzyme, on cardiac energy metabolism and function. METHODS AND RESULTS Transgenic mice constitutively overexpre...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2003
M Levin O Leppänen M Evaldsson O Wiklund G Bondjers T Björnheden

OBJECTIVE In large- and medium-sized arteries, the diffusion distances for oxygen and nutrients are long. This has been suggested to make these vessels prone to develop local energy metabolic deficiencies that could contribute to atherogenesis. To validate this hypothesis, we introduced a new method to measure energy metabolites within the arterial wall at high spatial resolution. METHODS AND...

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