An 8-year-old boy was admitted to the Ophthalmology Department due a vision impairment with an accompanying decrease in visual acuity and bilateral optic disc oedema. As result of interdisciplinary diagnostics, acute disseminated encephalomyelitis, probably related preceding infection, diagnosed.

Avian encephalomyelitis is caused by a Tremovirus and primarily affects chickens. The virus can infect young chicks and cause nervous symptoms. Vaccines are used to control the disease in breeders. Recently, the occurrence of the disease is causing concern in the poultry industry. In the present study, we report a case of avian encephalomyelitis in one broiler farm in Kashan (center of Iran). T...

The mononuclear phagocyte system, particularly dendritic cells, plays several pivotal roles in the development of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis. Here, we demonstrate that functionally distinct dendritic cell subpopulations are present in the central nervous system during experimental autoimmune encephalomyelitis. At peak experimental autoimmu...

Theiler's murine encephalomyelitis virus is an endemic murine pathogen that induces a demyelinating disease of the central nervous system in susceptible mouse strains. The disease is characterized by central nervous system mononuclear cell infiltration and presents as chronic, progressive paralysis. The expression of CC and C-x-C chemokines in the central nervous system of Theiler's murine ence...

Definition and history Inflammation of the brain can be caused by a number of diseases, but one of the preventable causes is viral infection. In addition to Rabies, with which most people have some familiarity, two other families of virus can cause brain infections in horses, resulting in what is commonly termed viral encephalitis. The first and older group is the Alphavirus family (previously ...

acute hemorrhagic leukoencephalitis (ahle) is a rare demyelinating disease characterized by an acute rapidly progressive fulminant inflammation of the white matter. in this case report, we introduce a case of ahle in children with an interesting and lengthy process and successful treatment. a previously healthy 13-year-old girl was admitted to the hospital because of fever and loss of conscious...

basic research on the autoimmune disease multiple sclerosis has been performed mainly on its animal model namely experimental allergic encephalomyelitis. there are many different approaches established to get this model. despite the existence of many references in literature in this regard, we have been faced with many difficulties generating the model suitable for studying different therapies....

multiple sclerosis (ms) is an autoimmune inflammatory demyelinating disease of the central nervous system. the aim of this study was to investigate the neuroprotective effects of transplanted human umbilical cord blood mesenchymal stromal cells (ucb-msc) derived neural progenitor cell (mdnpc) in eae, an experimental model of ms. to initiate neuronal differentiation of ucb-mscs, the pre-inductio...

It has previously been reported that synthetic peptides corresponding to sequences derived from T-cell receptor variable regions identified as dominant in the T-cell-mediated autoimmune disease experimental allergic encephalomyelitis in both the mouse and the rat can down-regulate disease in Lewis rats. In contrast to these results, we have found that immunization of Lewis rats with such peptid...