The objective of present work was to formulate and evaluate Fluconazole (FLZ) microsponges using quasi emulsion solvent diffusion technique and microsponge gel by using carbopol. Microsponges containing FLZ were obtained successfully with different proportions of ethyl cellulose polymer (EC). The formulations were studied for particle size and physical characterization. The physical characteriz...

Present investigation describes preparation of microspheres by solvent evaporation and W/O emulsion solvent evaporation methods followed by in vitro characterization of microspheres to evaluate the effect of method of preparation on physical properties and drug release profile of microspheres. The microspheres were found to be discrete, spherical with free flowing properties. The morphology (Sc...

Background Intravenous drug delivery is an advantageous choice for rapid administration, immediate drug effect, and avoidance of first-pass metabolism in oral drug delivery. In this study, the synthesis, formulation, and characterization of atorvastatin-loaded polyurethane (PU) nanoparticles were investigated for intravenous route of administration. Methods First, PU was synthesized and chara...

ber af problems fer nnr instantaneously While solvent-assisted emulsion systems have met with a degree of success in formulating pressure sensitive adhesives, they have several disadvantages. The solvent content of these systems precludes totally solvent-free adhesives. Also. there is reported evidence that surfactants used to stabilize the emulsion can adversely affect tack properties of the f...

Unloaded microspheres were prepared from polyhydroxybutyrate (PHB) and polyhydroxybutyrateco-valerate (PHB-HV) polymers using an oil-in-water emulsion solvent evaporation method. The study was conducted to evaluate how the polymer and some process parameters affect properties of the final microspheres such as particle size, superficial area, zeta potential, surface morphology and microsphere de...

Microspheres are one of the novel drug delivery system and are formulated conveniently to obtain prolonged or controlled drug delivery to enhance the bioavailability and target drug to the specific sites. Ritonavir loaded ethylcellulose buoyant microspheres were formulated using ethylcellulose as rate retarding material. Buoyant microspheres were formulated by emulsion solvent diffusion method....

objective(s) theophylline, a xanthenes derivative, is still widely used as an effective bronchodilator in the management of asthmatic patients. it is used both as a prophylactic drug and to prevent acute exacerbations of asthma. the aim of study was to formulate and evaluate effect of the microencapsulation of theophylline loaded nanoparticles on the reduction of burst release. materials and me...

conclusions according to release exponent n > 1, diffusion mechanism is super case п. the prepared micronized benzoyl peroxide in foamable formulation was stable according to different pharmaceutical evaluation. the emu oil incorporated in this formulation could reduce drawback of bpo (benzoyl peroxide). this formulation could be a good candidate in acne treatment. objectives benzoyl peroxide f...

Colour is one of the most important visual attributes of food and is directly related to the perception of food quality. The interest in natural colourants, especially β-carotene that not only imparts colour but also has well-documented health benefits, has triggered the research and development of different protocols designed to entrap these hydrophobic natural molecules to improve their stabi...

Supercritical fluids extraction of emulsions (SEE) is an innovative technique used for the production of micro, nano-particles with controlled size and distribution. Supercritical carbon dioxide (SC-CO2) is used to extract selectively the organic solvents from the droplets of the emulsion, in which the biopolymer is dissolved, producing the precipitation of the polymer and the subsequent format...