O ne way to attempt periodontal regeneration is to mimic the biologic processes involved in nascent tooth development, especially the development of the root and the supporting tissues. The EMDOGAIN® (BIORA AB, Malmö, Sweden) concept is based on the discovery that enamel matrix proteins are not only involved in enamel formation but also play a key role in the formation of acellular cementum [1,...

This study evaluates the effects of three kinds of periodontal surgery using statistical analyses of histological and immunohistochemical indices. Dehiscence defects were made on roots of maxillary teeth in monkeys. Surgically exposed roots were untreated, etched with EDTA, or treated with Emdogain® after EDTA etching. Paraffin sections were stained with hematoxylin and eosin or immunostained f...

The recession of the gingival margin is becoming a more prominent condition in the oral situation of many patients and should be treated at its earliest detection. The multifactorial etiology, decision modality, and current trends in the treatment of gingival recession are discussed in this article. The surgical technique of choice depends on several factors, but among the different surgical pr...

The objective of the current systematic review was to evaluate the efficacy of enamel matrix derivative (EMD) (Emdogain) on healing of replanted or autotransplanted permanent teeth. A review of the published literature [search term: (Emdogain OR enamel matrix derivative OR enamel matrix protein] AND [avulsion OR replantation OR autotransplantation)] was conducted by two independent investigator...

root resorption (rr) is defined as the loss of dental hard tissues because of clastic activity inside or outside of tooth the root. in the permanent dentition, rr is a pathologic event; if untreated, it might result in the premature loss of the affected tooth. several hypotheses have been suggested as the mechanisms of root resorption such as absence of the remnants of hertwig's epithelial root...