نتایج جستجو برای: embryonic ciliation
تعداد نتایج: 80499 فیلتر نتایج به سال:
The growth and development of colonial hydroids is dependent upon a flow of gastrovascular fluid through a common vasculature. Gastrovascular flow is believed to be driven by polyp contractions, stolonal contractions and endodermal ciliation. In the athecate hydroid Hydr•actinia symbiolongicarpus we found that polyp contractions, stolonal contractions and gastrovascular flow were only weakly co...
In this article, we give an overview of current research on shared secret-key agreement between two parties. This agree⁃ ment is based on radio wireless channel characteristics. We discuss the advantages of this approach over traditional cryp⁃ tographic mechanisms and present the theoretical background of this approach. We then give a detailed description of the key-agreement process and the th...
Wnt signaling is essential for the differentiation of airway epithelial cells during development. Here, we examined the role of Wnt signaling during redifferentiation of ciliated airway epithelial cells in vitro at the air liquid interface as a model of airway epithelial repair. Phases of proliferation and differentiation were defined. Markers of squamous metaplasia and epithelial ciliation wer...
Cilia and flagella are microtubule-based structures nucleated by modified centrioles termed basal bodies. These biochemically complex organelles have more than 250 and 150 polypeptides, respectively. To identify the proteins involved in ciliary and basal body biogenesis and function, we undertook a comparative genomics approach that subtracted the nonflagellated proteome of Arabidopsis from the...
In many arthropods, the appearance of new segments and their differentiation are not completed by end embryogenesis but continue, in different form degree, well after hatching, some cases up to last post-embryonic molt. Focusing on segmentation process currently described as segment addition (or, anamorphosis), we revise here current knowledge discuss it an evolutionary framework which involves...
Significance Mutations that activate LRRK2 protein kinase cause Parkinson's disease. phosphorylates a subset of Rab GTPases, in particular Rab8 and Rab10. We show here details related to the mechanism by which Rab10 phosphorylation blocks initiation cilia formation, fundamental information how pathogenic interferes with normal cell physiology.
Vertebrate centrioles normally propagate through duplication, but in the absence of preexisting centrioles, de novo synthesis can occur. Consistently, centriole formation is thought to strictly rely on self-assembly, involving self-oligomerization of the centriolar protein SAS-6. Here, through reconstitution of de novo synthesis in human cells, we surprisingly found that normal looking centriol...
Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a regulator of this process and cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood. Using Xenopus we show that Cp110 inhibits cilia formation at high levels, while optimal levels promote ciliogenesis. Cp110 localizes to cilia-forming basal bodies an...
Incisive canal cyst or nasopalatine duct cysts (NPDCs) are the most common nonodontogenic and developmental cysts of the maxilla. These developmental NPDC are usually asymptomatic and are discovered during routine radiological examination done for some other diagnosis. A cone-beam computed tomography (CBCT) is a valuable tool to localize a cyst within the nasopalatine canal. CBCT enables analys...
Primary cilium dysfunction underlies the pathogenesis of Bardet-Biedl syndrome (BBS), a genetic disorder whose symptoms include obesity, retinal degeneration, and nephropathy. However, despite the identification of 12 BBS genes, the molecular basis of BBS remains elusive. Here we identify a complex composed of seven highly conserved BBS proteins. This complex, the BBSome, localizes to nonmembra...
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