background: multiple factors have been suggested for prediction of pregnancy in intracytoplasmic sperm injection (icsi) cycles such as the number of injected oocytes, fertilization rate, embryo morphology and quality of transferred embryos. predictive value of these factors is important in icsi outcome. objectives: to evaluate the role of embryo morphology for prediction of pregnancy in icsi cy...

STUDY QUESTION Can the pronuclei (PN) morphology and the time of PN breakdown (PNB) predict the potential of embryos to result in live birth? SUMMARY ANSWER In comparison to embryos resulting in no live birth, PNB occurred significantly later in embryos resulting in live birth and never earlier than 20 h 45 min. None of the tested scoring systems were shown to predict the live birth outcome i...

OBJECTIVES In vitro maturation technique (IVM) is shown to have an effect on full maturation of immature oocytes and the subsequent embryo development. Embryonic genome activation (EGA) is considered as a crucial and the first process after fertilization. EGA failure leads to embryo arrest and possible implantation failure. This study aimed to determine the role of IVM in EGA-related genes expr...

BACKGROUND Embryos selection is crucial to maintain high performance in terms of pregnancy rate, reducing the risk of multiple pregnancy during IVF. Pronuclear and nucleolar characteristics have been proposed as an indicator of embryo development and chromosomal complement in humans, providing information about embryo viability. METHODS To correlate the zygote-score with the maternal age and ...

background: embryo selection is a vital part of in vitro fertilization (ivf) programs, with morphology-based grading systems having been widely used for decades. time-lapse imaging combined with embryo morph kinetics may proffer a non-invasive means for improving embryo selection. we report the first ongoing and chemical pregnancies using time-lapse embryo scope to select best embryos for trans...

Evaluation of fertility of living embryos is of practical importance in the daily routinesat fertility clinics and an ongoing biological research topic. Living embryos may be stud-ied through a light microscope. By focusing the microscope at different optical sections,the three-dimensional structure of the embryo may be studied. The purpose of the Ferti-morph project is to d...

Apart from the huge efforts made to develop an embryo in-vitro, the embryologist is faced with an even bigger task to choose an embryo from a cohort that will produce pregnancy. Selecting a single viable one is often a challenge to the embryologists and clinicians involved. This is because the one that is selected may determine outcome of the cycle. It is not in the embryologist interest to cho...