Elephantiasis of the external genitalia is characterized by lymphedema and thickening of the subcutaneous tissues. This gives the skin an appearance similar to a pachyderm skin. This pathology is invalidating for the patient. Reconstructive surgery is often the only way to restaure aesthetic and functional aspects of the external genitalia. We aim to report a 52 year man with huge penoscrotal e...

BACKGROUND Hydrocele and elephantiasis are 2 clinically very diverse and often mutually exclusive chronic manifestations of human bancroftian filariasis. Plasma levels of endothelin-1 (ET-1), a major angiogenic factor, and tumor necrosis factor receptors (TNFRs) that regulate host inflammation have been associated with development of chronic filariasis, although their genetic basis are not know...

Abdominal elephantiasis is a rare entity. Abdominal elephantiasis is an uncommon, but deformative and progressive cutaneous disease caused by chronic lymphedema and recurrent streptococcal or Staphylococcus infections of the abdominal wall. We present 3 cases of patients with morbid obesity who presented to our hospital with abdominal wall swelling, thickening, erythema, and pain. The abdominal...

A 53-year-old woman presented to the hospital complaining of severe pain in her right leg for the past several days. She has a 5-year history of lymphedema in her right leg, as well as morbid obesity, recurrent cellulitis, erysipelas, and osteomyelitis. She has never suffered from filariasis and has no family history of familial lymphedema. Her temperature on admission was 100.9◦F (38.3◦C). Exa...

Muitmalen Aji Moplah, Mussulman, aged 27 years, was admitted into the Calicut Civil Hospital, Malabar, August 12th 1873, with a scrotal tumour of enormous dimensions, reaching to within three inches of the ground as the man stood erect, fifteen years in growth. Patient's statement.?The tumour commenced in the scrotum, noticeable at first by a slight thickening of its coats, afterwards increasin...