A high-pressure electro-osmotic micro-pump fabricated by a sol-gel process is reported as a fluid-driving unit in a flow-injection analysis (FIA) system. The micro FIA system consists of a monolithic micro-pump on a glass slide (2.5 x 7.5 cm), a micro-injector, and a micro-sensor (2.5 x 1.5 cm). The monolithic silica matrix has a continuous skeleton morphology with micrometer-sized through-pore...

The spin-coating method, which is widely used for thin film device fabrication, is incapable of large-area deposition or being performed continuously. In perovskite hybrid solar cells using CH(3)NH(3)PbI(3) (MAPbI(3)), large-area deposition is essential for their potential use in mass production. Prior to replacing all the spin-coating process for fabrication of perovskite solar cells, herein, ...

An easy method for the determination of aflatoxins B1, B2, G1, and G2 in rhizosphere and rhizosplane of zea mays by LC coupled to mass spectrometry had been developed. Aflatoxins B1, B2, G1 and G2 in maize plants by LC coupled to mass spectrometry had been developed. Aflatoxins were extracted with a mixture of methanol and water and then it was purified by solid – phase clean – up using a polym...

The solubility behaviour of drug is one of the most challenging aspects in formulation development. Thus a greater understanding of dissolution and absorption behaviour of drug with low aqueous solubility is required to successfully formulate them into more soluble and hence bioavailable drug product. Therefore different approaches are being explored to enhance the solubility of poorly water so...

UNLABELLED Tetrahydropapaveroline and reticuline, isoquinoline alkaloids, were purified and identified in the pedal ganglia of the marine mollusk Mytilus edulis. OBJECTIVES To determine the presence of tetrahydropapaveroline and reticuline, isoquinoline alkaloids, in animal tissues previously shown to express opiate receptors. METHODS AND RESULTS This was achieved by high performance liquid...

Introduction The cornerstone of sepsis management requires identifying the causative pathogen and initiating appropriate antimicrobial therapy. Current pathogen detection relies on culture techniques, a technology that is over 100 years old, slow and unreliably. It is not unusual for only 10% of critical care blood cultures to be positive. Due to the low yield and time taken to obtain a result,...

Metal ion interactions with DNA have far-reaching implications in biochemistry and DNA nanotechnology. Ag(+) is uniquely interesting because it binds exclusively to the bases rather than the backbone of DNA, without the toxicity of Hg(2+). In contrast to prior studies of Ag(+) incorporation into double-stranded DNA, we remove the constraints of Watson-Crick pairing by focusing on homo-base DNA ...

The benzo annulated cycloheptatriene PCP pincer ligand was prepared in five steps. Treatment of with Ir(CO)3Cl gave the meridional cyclometalated chlorohydrido carbonyl iridium complexes which differ in their arrangement of the H, Cl, and CO ligands around iridium. Storing in THF led to isomerization processes. Hydrogen shifts from the sp(3)-CH carbon bound to iridium into the ligand backbone p...

Nuclear magnetic resonance (NMR) is a physical phenomenon based upon the quantum mechanical magnetic properties of an atoms nucleus. Thereby NMR spectroscopy is a technique to obtain physical, chemical and structural information about molecules. Recent research is focused on the analysis of small molecules, e.g. metabolites by NMR or in a combination of NMR and electro spray ionization mass spe...

Mass spectrometry (MS) is an analytical technique which is used to measure sample’s molecular mass by measuring mass to charge ratio. In this method, a soft ionization technique like ESI (Electro Spray Ionization) is used to generate charge ions. Now days, this is the most popular method for protein identification and quantitation. In shotgun proteomics proteins are digested into smaller peptid...