conclusions pmf-dependent efflux mechanism appears to play an important role in the mdr phenotype of a. baumannii clinical strains. background multidrug-resistant (mdr) strains of acinetobacter baumannii have been increasingly reported as a major cause of nosocomial infections, and have created major therapeutic problems worldwide. objectives the aim of the present study was to evaluate the rol...

background: this study aimed to evaluate the role of efflux pump regulator and oxa-23 genes in imipenem resistance acinetobacter baumannii strains isolated from hospitalized patients in tehran, iran. methods: this study was conducted on 60 a. baumannii isolates collected from patients admitted to the shahid motahari and taleghani hospitals in tehran during 2013-14. antibiotic susceptibility tes...

legionella pneumophila is the pathogen responsible for severe pneumonia known as legionnaires’ disease. legionella can live under varied stress conditions, especially in cold environments, and is common in many artificial environments. in this study, the antimicrobial activity of biogenic silver nanoparticles, prepared using the culture supernatant of klebsiella pneumoniae, was evaluated agains...

background: like several other parasites, teladorsagia circumcincta secretes or excretes urea, but nei-ther the rate of efflux nor the possible metabolic sources of the urea has been considered. methods: parasites were maintained by passage through sheep. urea efflux was measured using phe-nol/hypochlorite after treatment with urea aminohydrolase. the kinetics of creatine amidinohy-drolase and ...

Objective(s): Propofol (2, 6-diisopropylphenol) is an intravenous anesthetic that is commonly used for the general anesthesia. It is well known that the spinal cord is one of the working targets of general anesthesia including propofol. However, there is a lack of investigation of the effects of propofol on spinal dorsal horn which is important for the sensory transmission of nociceptive signal...

The key process in understanding carbon dynamics under different ecosystems is quantifying soil CO2 efflux. However, this can change annually as it depends on environmental variables. results of paper present the effects root network, temperature, and volumetric water content efflux, which were investigated Retisol two types land uses Western Lithuania 2017–2019: forest grassland. It was determ...

background: shigella spp. are gram negative bacteria, which are of global public health importance. the growing of multidrug-resistant shigella isolates are a major problemaround the world. methods: overall, 50 isolates of shigella spp. from children diarrheic stools were studied. the isolates were identified and confirmed using biochemical, serological and molecular methods (ipah, wbgz and rfc...

the drug pump protein mrp2 is a membrane drug efflux transporter widely distributed in normal and tumor tissues. its role is thought to be crucial for the disposition of many drugs and their substrates in different tissues. in this study, we aimed to examine the effects of systematic inflammation induced by lipopolysaccharide (lps) on the expression and function of this transporter in rats. jug...