A natural alkynol group-substituted thiophene, 2-(penta-1,3-diynyl)-5-(3,4-dihydroxybut-1-ynyl)-thiophene (PDDYT), was isolated from the roots of Echinops grijsii Hance. It possessed potent NAD(P)H: quinone oxidoreductase1 (NQO1) inducing activity and could activate Keap1-Nrf2 pathway effectively in murine hepatoma Hepa 1c1c7 cells. Further investigations indicated that the activation of Keap1-...

from flora of north west of iran, four contrasting species in term of frequency and coverage on heavy metal rich soils were selected to study physiological mechanisms for different tolerance of zn and cu toxicity in a hydroponic culture experiment. for study of zn toxicity, dactylis glomerata and secale monatum and for cu, cichorium intybus and astragalus echinops were selected. a clear differe...

Acanthus ilicifolius has long history of medicinal plant belong to the family Acanthaceae. In the present study, ethanolic extract of A. ilicifolius showed antitumour potential against HepG2 cell line induced hepatocarcinoma in mice. The phytochemical analysis were studied by using strandard methods. The heptocarcinoma mice were orally treated with extract of A.ilicifolius (500 mg/kg B.W). The ...

The species of Asteraceae were used traditionally in treatment of inflammatory disorders. The present study aimed to assess the anti-inflammatory effect of methanolic extract of aerial parts of Rhanterium epapposum Oliv. (R.epapposum), Achillea fragrantissima (Forssk.) Sch.Bip (A. fragrantissima), Artemisia herba-alba Asso. (A.herba-alba), Echinops spinosus L. (E. spinosus) and Echinops hussoni...

A new thiophene, echinothiophenegenol (1), together with seven known thiophenes was isolated from the crude ethanol extract of roots of Echinops grijisii Hance. The structure of 1 was elucidated on the basis of spectroscopic data. Compounds 2 and 5, isolated from the plant for the first time, and compounds 1-7 were tested for their cytotoxicity against two human cancer cell lines, HL60 and K562...

Echinops L., es un género de Asteraceae y contiene ca. 76 especies en Irán. La investigación actual se basa seis nueve poblaciones, incluidas E. cephalotus, chorassanicus, elebursessis, leiopolycerus, ritroides robustus. frecuencia distribución quiasmas, la asociación cromosómica segregación han sido analizadas para caracteres meióticos. En las estudiadas observado irregularidades meióticas, cr...