Uterine leiomyomas are highly prevalent benign tumors in reproductive aged women. Unfortunately, medical treatments are still limited and no preventive therapies have been developed. In the present study, we investigated the therapeutic effects of strawberry extract on uterine leiomyoma cells. Leiomyoma and myometrial cells were treated with strawberry (cultivar Alba) extract (250 μg/ml) for 48...

Background In CHO cell lines currently selected for the production of recombinant antibody, approximately 80% of the metabolized glucose is converted into lactic acid. These cells with a glycolytic phenotype exhibit significantly higher rates of proton production (extracellular acidification rate, ECAR) from lactate production than cells using oxidative phosphorylation (oxygen consumption rate,...

Bangladesh and neighboring areas face large health threats from drinking arseniccontaminated ground water. Arsenic levels in Bangladesh ground water are typically several hundred μg/L (compared to WHO recommendation of 10 μg/L for the MCL). About 50 million people drink such water, with hundreds of thousands already showing serious adverse health effects in what is described as the largest mass...

Equal channel angular rolling (ECAR) process is one of the severe plastic deformation (SPD) methods that have been used to make ultra-fine grain (UFG) materials with improving the mechanical properties of samples. After performing the process at several paths, a large strain is applied to the material that can cause decreasing the grain size and improving the mechanical and physical properties ...

BackgroundThe volatile anaesthetic sevoflurane protects cardiac tissue from reoxygenation/reperfusion. Mitochondria play an essential role in conditioning. We aimed to investigate how and its primary metabolite hexafluoroisopropanol (HFIP) affect necrosis, apoptosis, reactive oxygen species formation cardiomyocytes upon hypoxia/reoxygenation injury. Moreover, we describe the similarities mode o...

This article focuses on place-based pedagogy developed in partnership with Every Campus A Refuge (ECAR) at Guilford College, which is the first initiative of its kind to mobilize college and university campus resources provide housing other forms assistance refugees seeking resettlement institution’s local area (within beyond physical borders). ECAR transforming refugee United States as it also...

This study examines the action of the beta(3)-adrenoceptor antagonist SR59230A [3-(2-ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2S-2-propanoloxalate] at cloned mouse beta(3)-adrenoceptors expressed in Chinese hamster ovary cells (CHO-K1-beta(3)) or endogenously expressed in 3T3-F442A adipocytes or ileum. SR59230A displayed partial agonist properties compared with the beta(3)-adre...

abstract: the equal channel angular rolling (ecar) is one of the severe plastic deformation processes, which can develop a shear deformation into a sheet metal. in this process, internal stresses are created due to the different strain levels experienced in different locations at the same time. the incremental hole drilling method is an effective technique for the evaluation of the through-thic...

Abnormal cellular energetics has emerged as a hallmark of cancer cells. Deregulating aerobic glycolysis can alter multiple metabolic and signaling pathways in cancer cells, and trigger unlimited growth and proliferation. Accumulating evidence suggests that elevated levels of protein modification with β-N-acetylglucosamine (O-GlcNAcylation) along with dysregulation of O-GlcNAc transferase (OGT) ...

Using communication services is a common part of everyday life in a personal or business context. Communication services include Internet services like voice services, chat service, and web 2.0 technologies (wikis, blogs, etc), but other usage areas like home energy management and eMobility are will be increasingly tackled. Such communication services typically authenticate participants. For th...