نتایج جستجو برای: ebola virus

تعداد نتایج: 400131  

2016
Mory Keita Sophie Duraffour Nicholas J. Loman Andrew Rambaut Boubacar Diallo Nfaly Magassouba Miles W. Carroll Joshua Quick Amadou A. Sall Judith R. Glynn Pierre Formenty Lorenzo Subissi Ousmane Faye

In October 2015, a new case of Ebola virus disease in Guinea was detected. Case investigation, serology, and whole-genome sequencing indicated possible transmission of the virus from an Ebola virus disease survivor to another person and then to the case-patient reported here. This transmission chain over 11 months suggests slow Ebola virus evolution.

2015
Athalia Christie Gloria J. Davies-Wayne Thierry Cordier-Lasalle David J. Blackley A. Scott Laney Desmond E. Williams Shivam A. Shinde Moses Badio Terrence Lo Suzanne E. Mate Jason T. Ladner Michael R. Wiley Jeffrey R. Kugelman Gustavo Palacios Michael R. Holbrook Krisztina B. Janosko Emmie de Wit Neeltje van Doremalen Vincent J. Munster James Pettitt Randal J. Schoepp Leen Verhenne Iro Evlampidou Karsor K Kollie Sonpon B. Sieh Alex Gasasira Fatorma Bolay Francis N. Kateh Tolbert G. Nyenswah Kevin M. De Cock

On March 20, 2015, 30 days after the most recent confirmed Ebola Virus Disease (Ebola) patient in Liberia was isolated, Ebola was laboratory confirmed in a woman in Monrovia. The investigation identified only one epidemiologic link to Ebola: unprotected vaginal intercourse with a survivor. Published reports from previous outbreaks have demonstrated Ebola survivors can continue to harbor virus i...

Journal: :The Lancet. Global health 2016
Moses J Soka Mary J Choi April Baller Stephen White Emerson Rogers Lawrence J Purpura Nuha Mahmoud Christine Wasunna Moses Massaquoi Neetu Abad Jomah Kollie Straker Dweh Philip K Bemah Athalia Christie Victor Ladele Oneychachi C Subah Satish Pillai Margaret Mugisha Jonathan Kpaka Stephen Kowalewski Emilio German Mark Stenger Stuart Nichol Ute Ströher Kristin E Vanderende Shauna Mettee Zarecki Hugh Henry W Green Jeffrey A Bailey Pierre Rollin Barbara Marston Tolbert G Nyenswah Alex Gasasira Barbara Knust Desmond Williams

BACKGROUND Ebola virus has been detected in semen of Ebola virus disease survivors after recovery. Liberia's Men's Health Screening Program (MHSP) offers Ebola virus disease survivors semen testing for Ebola virus. We present preliminary results and behavioural outcomes from the first national semen testing programme for Ebola virus. METHODS The MHSP operates out of three locations in Liberia...

2015
Kyle Bibby Robert J. Fischer Leonard W. Casson Elyse Stachler Charles N. Haas Vincent J. Munster

In the wake of the ongoing 2014/2015 Ebola virus outbreak, significant questions regarding the appropriate handling of Ebola virus-contaminated liquid waste remain, including the persistence of Ebola virus in wastewater. To address these uncertainties, we evaluated the persistence of Ebola virus spiked in sterilized domestic sewage. The viral titer decreased approximately 99% within the first t...

2015
Guojing Wang Yu Sun Kuo Zhang Tingting Jia Mingju Hao Dong Zhang Le Chang Lei Zhang Rui Zhang Guigao Lin Rongxue Peng Jinming Li Jens H. Kuhn

In 2014, Ebola hemorrhagic fever broke out in West Africa. As contact between China and West Africa is frequent, the possibility that Ebola virus would enter China was high. Thus, an external assessment of the quality of Ebola virus detection was organized by the National Center for Clinical Laboratories in China. Virus-like particles encapsulating known sequences of epidemic strains of Ebola v...

2017
Luke Nyakarahuka Eystein Skjerve Daisy Nabadda Doreen Chilolo Sitali Chisoni Mumba Frank N Mwiine Julius J Lutwama Stephen Balinandi Trevor Shoemaker Clovice Kankya

BACKGROUND Uganda has reported five (5) Ebola virus disease outbreaks and three (3) Marburg virus disease outbreaks from 2000 to 2016. Peoples' knowledge and attitude towards Ebola and Marburg virus disease impact on control and prevention measures especially during outbreaks. We describe knowledge and attitude towards Ebola and Marburg virus outbreaks in two affected communities in Uganda to i...

2017
Lawrence J. Purpura Emerson Rogers April Baller Stephen White Moses Soka Mary J. Choi Nuha Mahmoud Christine Wasunna Moses Massaquoi Jomah Kollie Straker Dweh Philip Bemah Victor Ladele Jonathan Kpaka Mary Jawara Margaret Mugisha Onyekachi Subah Mylene Faikai Jeff A. Bailey Pierre Rollin Barbara Marston Tolbert Nyenswah Alex Gasasira Barbara Knust Stuart Nichol Desmond Williams

Ebola virus is known to persist in semen of male survivors of Ebola virus disease (EVD). However, maximum duration of, or risk factors for, virus persistence are unknown. We report an EVD survivor with preexisting HIV infection, whose semen was positive for Ebola virus RNA 565 days after recovery from EVD.

Journal: :Science 2015
Yasuteru Sakurai Andrey A Kolokoltsov Cheng-Chang Chen Michael W Tidwell William E Bauta Norbert Klugbauer Christian Grimm Christian Wahl-Schott Martin Biel Robert A Davey

Ebola virus causes sporadic outbreaks of lethal hemorrhagic fever in humans, but there is no currently approved therapy. Cells take up Ebola virus by macropinocytosis, followed by trafficking through endosomal vesicles. However, few factors controlling endosomal virus movement are known. Here we find that Ebola virus entry into host cells requires the endosomal calcium channels called two-pore ...

Journal: :The Journal of general virology 1999
V E Volchkov V A Volchkova A A Chepurnov V M Blinov O Dolnik S V Netesov H Feldmann

The nucleotide sequences of the L gene and 5' trailer region of Ebola virus strain Mayinga (subtype Zaire) have been determined, thus completing the sequence of the Ebola virus genome. The putative transcription start signal of the L gene was identical to the determined 5' terminus of the L mRNA (5' GAGGAAGAUUAA) and showed a high degree of similarity to the corresponding regions of other Ebola...

Journal: :MMWR. Morbidity and mortality weekly report 2016
Charles Alpren Michelle Sloan Karen A Boegler Daniel W Martin Elizabeth Ervin Faith Washburn Regan Rickert Tushar Singh John T Redd

On January 14, 2016, the Sierra Leone Ministry of Health and Sanitation was notified that a buccal swab collected on January 12 from a deceased female aged 22 years (patient A) in Tonkolili District had tested positive for Ebola virus by reverse transcription-polymerase chain reaction (RT-PCR). The most recent case of Ebola virus disease (Ebola) in Sierra Leone had been reported 4 months earlie...

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