Onychomycosis, the fungal infection of nail is a common occurrence. The conventional fungi implicated are dermatophytes and Candida species. Non-dermatophytic moulds account for few cases and Chaetomium globosum is an exceptional agent. This characteristically involves the toe nails which are dystrophic and discoloured yellow-brown. Direct microscopy shows brown septate hyphae. Isolate is rapid...

INTRODUCTION Hay Wells syndome, also known as ankyloblepharon–ectodermal dysplasia–clefting (AEC) syndrome, is one of the ectodermal dysplasia syndromes. It is an autosomal dominant disorder characterized by findings of ectodermal dyplasia including alopecia, scalp infections, dystrophic nails, hypodontia, ankyloblepharon and cleft lip-palate (1). It was first described by Hay and Wells in 7 in...

I RECENT months there has been made available plastic material which can be fashioned into artificial “finger-nails” that are advertised “for those who want long nails.” In addition, the plastic nails may be used by persons who wish to disguise dystrophic or diseased nails or who wish to discourage nail, biting. This plastic material is essentially the same as that used in acrylic dentures, and...

Dyskeratosis congenita (DC) is a rare hereditary disorder characterized by bone marrow failure, cancer predisposition (11-fold increase compared to general population), ectodermal dysplasia (nail dystrophy, oral leukoplakia, and abnormal skin pigmentation) and other additional somatic abnormalities. A 22-year-old man presented with fever, chills, and a painful throat. Leukoplakia was noted on h...

Onychomycosis is a relatively common dermatologic presentation (Table 1). The incidence of the disease varies regionally and with age. Although in most cases the condition poses no significant long-term health risk, treatment is indicated. Affected nails can be cosmetically unsightly and may become painful and cause functional impairment. In some cases, such as among diabetic patients, treatmen...

A mycological study of onychomycosis was undertaken in 88 patients. The nails were judged to be infected by their clinical appearance. Direct microscopy of the nail clips in 20% KOH solution was positive in 72 (81.8%) and culture was positive in 43 (48.8%) cases. Out of the samples cultured, dermatophytes were grown in 26 cases (29.5%), non dermatophyte moulds in 12 (13.6%) and Candida spp. in ...

Pachyonychia congenita (PC) is a rare genodermatosis caused by mutations in any of the four genes KRT6A, KRT6B, KRT16, or KRT17, which can lead to dystrophic, thickened nails and focal palmoplantar keratoderma, among other manifestations. Although classically subdivided into two major variants, PC-1 (Jadassohn-Lewandowski syndrome) and PC-2 (Jackson-Lawler syndrome), according to the localizati...

Background. Darier's disease (DD), also known as Keratosis Follicularis or Darier-White disease, is a rare disorder of keratinization. DD can present as a generalized autosomal dominant condition as well as a localized or segmental postzygotic condition (Vázquez et al., 2002). Clinical features of DD include greasy, warty papules and plaques on seborrheic areas, dystrophic nails, palmo-plantar ...

A54-year-old woman was referred for evaluation of possible cor pulmonale based on the presence of dyspnea, chronic productive cough, and bilateral leg edema for 8 years. For about 8 years, her nails had been thick, brown-yellowish and would break easily. The nail grew very slowly and sometimes separated from its bed. The appearance of the nails did not change after 7 courses of antimycotic ther...

Case A 50 year old male, known HIV patient on ART for past 4 months, presented with complaints of scaly raised lesions over palms, soles and genitalia with history of burning micturition and swelling of right knee for over one month. On examination patient was thin built, anaemic. Right knee joint effusion with tenderness was present. Palms and soles revealed keratoderma blenorrhagicum. Nails w...