Dysarthria is present in 23 51% of multiple sclerosis (MS) patients, and the perceived characteristics of dysarthria have been shown to predict quality of life in these individuals. Tests of maximum performance such as oral diadochokinesis and Sequential Motion Rates (SMRs) are used in many neurology clinics and are considered to be sensitive indices of dysarthria. This large scale study invest...

Dysarthria is a frequent symptom in cerebral ischaemia. However, speech characteristics of these patients have not previously been investigated in relation to lesion site in a prospective study. We investigated the auditory perceptual features in 62 consecutive patients with dysarthria due to a single, non-space-occupying cerebral infarction confirmed by MRI. Standardized speech samples of all ...

BACKGROUND AND PURPOSE Isolated dysarthria, termed pure dysarthria, develops rarely after stroke, and its pathophysiology remains unclear. To clarify the underlying mechanism of pure dysarthria, we investigated lesion sites and cerebral blood flow in patients with pure dysarthria. METHODS We examined 12 patients with pure dysarthria who underwent MRI and cerebral blood flow study. To visualiz...

Pediatric traumatic brain injury (TBI) may result in long-lasting language impairments alongside dysarthria, a motor-speech disorder. Whether this co-morbidity is due to the functional links between speech and language networks, or to widespread damage affecting both motor and language tracts, remains unknown. Here we investigated language function and diffusion metrics (using diffusion-weighte...

Parkinsonian dysarthria is generally known under the name of hypokinetic dysarthria. Dysarthria, according to Darley et al (1969), is characterized by all speech disorders related to disturbances of muscular control of the speech organs, whose origin is a central or peripheral nervous system injury. So we must understand by dysarthria all failures related to either different levels of speech pr...

INTRODUCTION Skeletal muscle is common in late-onset Pompe disease (LOPD). Recent data implicate common bulbar muscle involvement (i.e., the tongue). METHODS We used quantitative assessment of lingual strength to retrospectively determine the frequency and severity of lingual weakness in LOPD. We additionally examined associations between lingual strength and the presence or absence of dysart...

The current study investigated the processes responsible for selection of sounds and syllables during production of speech sequences in 10 adults with hypokinetic dysarthria from Parkinson's disease, five adults with ataxic dysarthria, and 14 healthy control speakers. Speech production data from a choice reaction time task were analyzed to evaluate the effects of sequence length and practice on...