We report a facile approach to forming dendrimer-stabilized gold nanoparticles (Au DSNPs) through the use of amine-terminated fifth-generation poly(amidoamine) (PAMAM) dendrimers modified by diatrizoic acid (G5.NH(2)-DTA) as stabilizers for enhanced computed tomography (CT) imaging applications. In this study, by simply mixing G5.NH(2)-DTA dendrimers with gold salt in aqueous solution at room t...

BACKGROUND Reduced risk of paraplegia is argued as an advantage of endovascular repair of descending thoracic aortic aneurysms (DTA) and thoracoabdominal aortic aneurysms (TAAA); however, paraplegia rates with open repair vary widely. STUDY DESIGN We identified consecutive patients undergoing open repair of TAAA or DTA with or without arch replacement using profound hypothermia and circulator...

The objective was to characterize the ability of control and transgenic brown adipose tissue (BAT)-ablated uncoupling protein diphtheria toxin A chain (UCP-DTA) mice to adjust food intake in relation to changes in environmental temperature and to assess the involvement of leptin in this adjustment. We measured serum leptin in mice from a previous study of UCP-DTA mice raised at thermoneutrality...

We describe a technique that maps unranked trees to their hash codes using a bottom-up deterministic tree automaton (DTA). In contrast to techniques implemented with minimal tree automata, our procedure builds a pseudo-minimal DTA. Pseudo-minimal automata are larger than the minimal ones but in turn the mapping can be arbitrary, so it can be determined prior to the automaton construction. We al...

Recent advances in Immuno-Oncology (IO) have shown that the immune system can be activated to induce long term durable anti-tumor responses. For IO drug development, immune activation is typically explored using rat surrogate antibodies in immunocompetent mouse models. While these models can be used to show efficacy in vivo, the development of anti-drug immune responses to experimental protein-...

15 2DTA 2NTA NTA p MITL k U k DTA Figure 5: Relationship between various classes Theorem 5.2 The membership problem for 2NTA is solvable in PSPACE. Proof. Consider a 2NTA A, and let k be the magnitude of the largest constant appearing in a clock constraint in the transitions of A. Given a timed word w = (;) of length n, deene R w to be the set comprising of i + c and (i + j + c)=2 for 1 i; j n ...

AIM To investigate the reproducibility of the updated Standards for the Reporting of Diagnostic Accuracy Studies tool (STARD 2015) in a set of 106 studies included in a Cochrane diagnostic test accuracy (DTA) systematic review of imaging tests for diagnosing manifest glaucoma. METHODS One senior rater with DTA methodological and clinical expertise used STARD 2015 on all studies, and each of t...

OBJECTIVE To investigate diagnostic test accuracy (DTA) of different tests for obstructive sleep apnea (OSA) compared to polysomnography (PSG) in children. METHODS We performed a systematic review according to DTA criteria published by the Cochrane Collaboration. Studies that compared any possible diagnostic test with PSG for diagnosing OSA were considered. Study quality assessment was conduc...

To determine the ability of two-dimensional echocardiography (2-D echo) to detect aneurysms and dissections of the descending thoracic aorta (DTA), we studied 15 patients, five with proved DTA dissections (group A) and 10 with proved aneurysms without dissection (group B), using 2-D echo in three recording positions: precordial, suprasternal and a modified apical. The DTA was visualized in 14 o...

Dynamic traffic assignment (DTA) has been a topic of substantial research during thepast decade. While DTA is gradually maturing, many aspects of DTA still needimprovements, especially regarding its formulation and solution capabilities under thetransportation environment impacted by the Advanced Transportation Management andInformation Systems (ATMIS). It is necessary to develo...