A service evaluation of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing and result notification in patients attending a rapid testing service (Dean Street Express [DSE]) compared with those attending an existing 'standard' sexual health clinic (56 Dean Street [56DS]), and modelling the impact of the new service from 1 June 2014 to 31 May 2015. PRIMARY OUTCOME time from patie...

BACKGROUND Rational synthesis of novel structures resulted in two unique molecules (DSE-36 and DSE-37, disulphide esters of carbothioic acid) that killed sperm 25 times more strongly and with a precisely targeted action than nonoxynol-9 (N-9). We examine the effects of DSE-36 and DSE-37 on human spermatozoa versus HeLa cells to establish specificity and safety compared with N-9. METHODS AND R...

BACKGROUND Dermatan sulfate (DS) is a highly sulfated polysaccharide with a variety of biological functions in extracellular matrix organization and processes such as tumorigenesis and wound healing. A distinct feature of DS is the presence of iduronic acid, produced by the two enzymes, DS-epimerase 1 and 2, which are encoded by Dse and Dsel, respectively. METHODS We have previously shown tha...

OBJECTIVE To compare the relative accuracy of dobutamine stress echocardiography (DSE) and quantitative technetium-99m sestamibi single photon emission computed tomography (mibi SPECT) for detecting infarct related artery stenosis and multivessel disease early after acute myocardial infarction. DESIGN Prospective study. SETTING University hospital. METHODS 75 patients underwent simultaneo...

AIMS Although dobutamine stress echocardiography (DSE) is an accepted tool for the diagnosis of coronary artery disease (CAD), it requires subsequent image acquisitions of the left ventricle (LV) in order to visualize all segments. This makes the procedure relatively time-consuming and might limit its accuracy. With the introduction of matrix array transducers, the real-time simultaneous acquis...

Objective: To determine the safety and cardiac chronotropic responsiveness to early atropine dobutamine stress echocardiography (DSE) in the elderly. Design: Retrospective study of 258 patients > 70 years who underwent early atropine DSE and 290 patients> 70 years who underwent conventional DSE. In the early atropine protocol, atropine was started at 20 mg/kg/min of dobutamine if heart rate was...

OBJECTIVE To determine the safety and cardiac chronotropic responsiveness to early atropine dobutamine stress echocardiography (DSE) in the elderly. DESIGN Retrospective study of 258 patients >or= 70 years who underwent early atropine DSE and 290 patients >or= 70 years who underwent conventional DSE. In the early atropine protocol, atropine was started at 20 microg/kg/min of dobutamine if hea...

Coupled volume spaces are typically defined as a main volume connected to an auxiliary volume through an acoustically transparent aperture. Given certain architectural parameters, coupled volumes can exhibit a non-exponential sound energy decay, referred to in this paper as double slope effect (DSE). This paper provides an overview and comparison of several quantifiers of DSE. Four numeric DSE ...

Preface Designing Screening Experiments (DSE) is a class of information-theoretical models for multiple-access channels (MAC). In Sect. 2-4, we discuss the combinatorial model of DSE called a disjunct channel model. This model is the most important for applications and closely connected with the superimposed code concept. In Sect. 2, we give a detailed survey of lower and upper bounds on the ra...

PURPOSE To compare the value of Dobutamine stress echocardiography (DSE) with that provided by Dobutamine Cardiac Magnetic Resonance (DCMR) for the non-invasive risk stratification of patients with suspected or known coronary artery disease (CAD). METHODS Patients with suspected or known CAD underwent either DSE or DCMR using the same standardized protocol. Patient matching was then performed...