Thiamine deficiency and beriberi are prevalent in Cambodia, although most infants with nonspecific clinical symptoms of beriberi, including tachypnea, lack echocardiographic evidence diagnostic of the disease. Camphor activates transient receptor potential vanilloid 3 (TRPV3), a nonselective ion channel expressed in the medial preoptic nucleus of the hypothalamus and thought to be important for...

Case: We describe a case of beriberi with leg edema, pleural effusion, and anemia. Echocardiography revealed that the inferior vena cava diameter was 18 mm, but respiratory changes were not observed. Pulmonary hypertension was observed, with a systolic pulmonary arterial pressure of 45 mmHg. Peripheral blood concentrations of vitamin B1 decreased significantly. Beriberi heart disease caused by ...

a large number have come under my observation. As the signs, symptoms and apparent causation of the disease agreed in many instances with Morehead's description of Beriberi, I had begun to regard the outbreak as one of veritable beriberi; and some of the last cases that occurred amongst the men of my regiment I entered under this heading. As Morehead's book may not be in every one's hands, I he...

RATIONALE Circulatory failure, especially with low systemic vascular resistance (SVR), as observed in septic shock, thyrotoxicosis, and anemia, is a particular pattern that should suggest thiamine (vitamin B1) deficiency. The clinical picture of wet beriberi secondary to thiamine deficiency only demonstrates non-specific clinical manifestations. For a diagnosis of wet beriberi, medical history ...