background:  infections  in  neutropenic  patients  are  considered  as  major  causes  of  mortality and the emergence of drug resistance. gram positive bacterial infections are crucially important to be covered if indicated. vancomycin is active against most gram positive bacteria including methicillin resistant staphylococcus aureus (mrsa). in this study, we evaluated the appropriate utiliza...

background: opioid drugs are the most effective drugs for the treatment of moderate to severe pain. rates of opioid use are influenced by a variety of factors. the aim of this study was to determine the pattern of use of parenteral opioid drugs in hospitalized patients in a referral teaching hospital. methods: in a retrospective study, required data were extracted from medical records of adult ...

background and objectives: the expanding field of psychopharmacology is constantly seeking new and improved drugs to treat psychiatric disorders. although psychotropic drugs have had a remarkable impact in psychiatry, their utilization, effectiveness, and side effects in the in clinical practice need continuous study. the present study was thus designed to analyze the pattern of psychotropic dr...

drug utilization evaluation (due) studies facilitate assessing the appropriateness and rational use of medications.the goal of the present study was to evaluate amphotericin b usage in neutropenic patients. a prospective due study was performed in hematology-oncology and stem cell transplantation wards at taleghani hospital for one-year. national comprehensive cancer network, clinical practice ...

As policymakers debate adding a prescription drug benefit to Medicare, they must also seek ways to promote cost-effective use of drugs and minimize inappropriate prescribing. For more than a decade, all state Medicaid agencies and most private insurers have used computerized drug utilization review (DUR) programs to prevent or rectify potential prescribing errors. DUR can be retrospective, in w...

background: granulocyte colony stimulating factors (gcsf) are high cost agents commonly recommended for primary and secondary prophylaxis of chemotherapy-induced neutropenia and febrile neutropenia. gcsfs have been shown to be beneficial in some patient subgroups, although they are probably overused in clinical settings. the american society of clinical oncology (asco) guidelines summarize curr...

BACKGROUND The Omnibus Budget Reconciliation Act of 1990 offered the promise that prospective drug utilization review (pDUR) systems would improve the quality of drug prescribing and patient drug use. There is little evidence that this promise has been fulfilled. To the contrary, there is growing evidence that suboptimal use of drugs (in terms of preventable drug-related morbidity) is at least ...

Hypertension is chronic disease with high prevalence, which can successfully be treated with antihypertensive drugs. Previous researches have shown that existing hypertension treatment guidelines are not fully implemented in practice. We have analysed antihypertensive drug utilization in Canton Sarajevo during five-year period (2004-2008). Research findings are discussed in relation to expected...

During past few years numerous research studies have been conducted worldwide to determine the safe and effective drug utilization indicating that inappropriate drug use is a universal phenomenon [1]. Trend of drug utilization studies is raised globally in different health setups to examine the use of drugs in a society. This results in enormous social, economic and medical significance. Such t...