conclusions the present study showed a high prevalence of aminoglycoside-resistance genes among mrsa isolates in two cities in iran. results the results of drug susceptibility testing showed that the highest rate of resistance was against erythromycin in tehran (84.4%) and gentamicin (71.7%) in sari. all isolates were sensitive to vancomycin, and all strains harbored the meca gene. the aac (6’)...

Chromoblastomycosis is a chronic granulomatous infection caused by dematiaceous fungi with varied clinical presentations, which may represent therapeutic challenge. In this report, we present case of chromoblastomycosis in localized form, long evolution, an elderly patient, resistant to previous drug therapies, successfully treated the association physical method systemic pharmacological treatm...

Studying drug resistance in Plasmodium falciparum requires accurate measurement of parasite response to a drug. Factors such as mixed infection of drug-resistant and -sensitive parasites can influence drug test outcome. Polymorphic DNA sequences are frequently used to detect mixed infections; infections with a single genotype or having a minor allele smaller than a subjectively selected cut-off...

Consultant Paediatric neurologist, King Fahad Military Hopsital, Jeddah21159, Saudi Arabia E-mail: [email protected]; Tel: 00966 535556205 Managing Acinetobacter baumannii infection is challenging during the treatment of infected ventriculoperitoneal shunt due to its propensity to develop multi drug resistance (MDR) to commonly used potent antibiotics in hospital settings. We present one such...

conclusions all the staphylococcus aureus strains and enterococcus faecium strains were sensitive to members of the oxazolidinone class of linezolid drug. development of multi drug resistance by gram positive bacteria constitutes a very serious challenge for medical practice. despite these rising rates, it is impossible to distinguish where they have originated from and special attention has th...

BACKGROUND The growing burden of neonatal mortality associated with hospital-acquired neonatal sepsis in the developing world creates an urgent need for cost-effective infection-control measures in resource-limited settings. METHODS Using a before-and-after comparison design, we measured how rates of staff hand-hygiene compliance, colonization with drug-resistant pathogens (defined as ceftazi...

Since the discovery of the first strain in 1961 in England, MRSA, the most notorious multidrug-resistant hospital pathogen, has spread all over the world. MRSA repeatedly turned down the challenges by number of chemotherapeutics, the fruits of modern organic chemistry. Now, we are in short of effective therapeutic agents against MRSA prevailing among immuno-compromised patients in the hospital....

b a ckground: s taphylococcus aureus (s. aureus) has remained always an important pathogen of common infections acquired in community and as  well as serious nosocomial infections. with advent of penicillins and cephalosporins, infections could be effectively treated, but with the global emergence of methicillin resistant staphylococcus aureus strains (mrsa) physicians were  again left  with li...

Early initiation of antiretroviral therapy (ART) reduces the risk of drug-sensitive HIV transmission but may increase the transmission of drug-resistant HIV. We used a mathematical model to estimate the long-term population-level benefits of ART and determine the scenarios under which earlier ART (treatment at 1 year post-infection, on average) could decrease simultaneously both total and drug-...