concomitant use of several drugs by icu( intensive care unit) patients is often unavoidable. in these patients, pharmacokinetic drug interactions are very likely. the current study was designed to evaluate these interactions in patients hospitalized in an icu of a teaching hospital in tehran, iran. a questionnaire was designed and used to collect study data. the study was done in the icu of a t...

background : proton pump inhibitors (ppis) are currently the most effective agents for acid related disorders. however, studies show that 25-75% of patients receiving intravenous pantoprazole had no appropriate justification, indicating high rate of inappropriate prescribing in hospitals. the aim of this study is to examine the appropriate use of intravenous pantoprazole in accordance with guid...

OBJECTIVES The objective of this investigation was to demonstrate the possibility of the construction of a real-time prescription drug monitoring system (PDMOS) using data from the nationwide Drug Utilization Review (DUR) system in Korea. METHODS The DUR system collects information on drug prescriptions issued by healthcare practitioners and on drugs dispensed by pharmacies. PDMOS was constru...

INTRODUCTION The expected therapeutic response may be affected by the presence of drug interactions. With the high number of reports on new drug interactions, it has been difficult for health professionals to keep constantly updated. For this reason, computer systems have helped identify such interactions. OBJECTIVES To verify the rate and profile of drug interactions in medical prescriptions...

OBJECTIVE RxNorm is a standardized drug nomenclature maintained by the National Library of Medicine that has been recommended as an alternative to the National Drug Code (NDC) terminology for use in electronic prescribing. The objective of this study was to evaluate the implementation of RxNorm in ambulatory care electronic prescriptions (e-prescriptions). METHODS We analyzed a random sample ...

Lopinavir/ritonavir forms part of the antiretroviral therapy for the treatment of human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). The aim of this non-experimental, quantitative drug-utilization study was to determine and identify potential drug-drug interactions between lopinavir/ritonavir and other antiretrovirals in general practitioners and specialists prescripti...