The purpose of this research was to develop a matrix-type transdermal therapeutic system containing drug Diclofenac acid, Pressure Sensitive Adhesive (PSA) like acrylic adhesive by the solvent evaporation technique. Different concentrations of Labrasol, oleic acid and triacetin were used to enhance the transdermal permeation of diclofenac acid. Polyethylene monolayer film as a backing membrane ...

abstract statement of problem: the viscosity of orthodontics adhesive primers is crucial for stability and correct brackets ‘position during bond up. an excessive adhesive flow during brackets seating could change the brackets’ position. objectives: the main purpose of this study was to investigate the viscosity of four orthodontic adhesive primers in two different temperatures. materials and m...

Objective: To analyse hospital costs in the pre-, and intraand post-operative periods associated with patients undergoing rectal resection with anastomosis, comparing the costs per patient with and without the use of fibrin-based biological adhesive(Tissucol Duo ® ). Methods: The cost analysis was designed with a subsample of 37 patients who underwent rectal anastomosis in a randomised, single-...

Objective: The objective of the present work aims to check effect penetration enhancers on release kinetics in a novel drug adhesive transdermal system furosemide. Methods: systems were evaluated for pharmacotechnical properties and vitro permeation through excised rat epidermis. Among DURO-TAKs screened studies. results quantified using RP-HPLC. optimized was subjected vivo kinetic studies New...

In this study, a novel 5-Fluorouracil (5-FU) enema with good bio adhesion and temperature sensitivity was developed using in situ gelling technology. The preparation was formulated as a free-flowing liquid before use, while a layer of gel film was quickly formed when administered in the rectum, with a large contact surface area. It also demonstrated good biocompatibility, appropriate gel streng...

Urinary tract infections (UTIs) are one of the most common bacterial infections, affecting 150 million people each year worldwide. High recurrence rates and increasing antimicrobial resistance among uropathogens are making it imperative to develop alternative strategies for the treatment and prevention of this common infection. In this Review, we discuss how understanding the: (i) molecular and...

In this study, we report the development of all-solution-processed multifunctional organic bioelectronics, comprising reduced graphene oxide (rGO) and dexamethasone 21-phosphate disodium salt (DEX) drug loaded poly(3,4-ethylenedioxythiophene) (PEDOT) microelectrode arrays on indium tin oxide glass, that can be used to manipulate human mesenchymal stem cell (hMSC) spreading morphology on rGO mic...

Background: The clinical success of sandwich technique depends on the strength of resin-modified glass ionomer cement (RMGIC) bonding to both dentin and resin composite. Therefore, the shear bond strength (SBS) of resin composite bonded to RMGIC utilizing different resin adhesives versus a GIC-based adhesive was compared. Materials and methods: In this in vitro study, 84 holes (5×2 mm) were pre...