Several studies suggest a high comorbidity of substance abuse and schizophrenia, associated with higher frequency of relapse, more positive symptoms and depression, cognitive impairment, poorer outcome and treatment response. A high incidence of substance abuse is also observed in first-episode patients. Among patients with substance abuse, the onset precedes the onset of psychosis of several y...

Drug abuse is one of the global issues and has spread among teenagers. Drugs may lead to subordination, health problems even death. There are several policies made in each country related problem drug abuse, both punishment treatment. In this paper, we discuss treatment strategy reduce number users. users can recover themselves by undergoing rehabilitation form inpatient or outpatient care. We ...

OBJECTIVE To (a) describe the demographics of opioid abusers; (b) compare the prevalence rates of selected comorbidities and the medical and drug utilization patterns of opioid abusers with patients from a control group, for the period from 1998 to 2002; and (c) calculate the mean annual per-patient total health care costs (e.g., inpatient, outpatient, emergency room, drug, other) from the pers...

results results showed that there was a significant difference between the experimental and control groups in terms of depression and temping beliefs (p < 0.0001). in other words, the results showed that cognitive-behavior therapy reduces depression and improves craving beliefs of abusers under methadone maintenance treatment. objectives this study aimed at investigating the effectiveness of co...

The Addiction-Stroop test has been widely used to investigate the attentional correlates of alcohol and drug abuse; however, the majority of the studies have been conducted with European and American participants. The present study tested whether Iranian drug abusers show higher attentional bias for drug-related stimuli. Participants included drug abusers (N = 53; 100% male), with a clinical hi...

BACKGROUND Deaths caused by drug abuse, in which the cause of death is intoxication, so-called overdose deaths, are regularly reported and studied. Other deaths related to drug abuse have been less frequently studied. We wished to investigate the prevalence and characteristics of unnatural deaths in persons in whom drugs were detected in blood samples taken at autopsy. MATERIAL AND METHOD A t...

Telomeres are protective chromosomal structures that play a key role in preserving genomic stability. Telomere length is known to be associated with ageing and age-related diseases. To study the impairment of telomeres induced by drug abuse, we conducted an association study in the Chinese Han population. Multivariate linear regression analyses were performed to evaluate the correlation of leuk...

There is emerging evidence that suggests emotional processes may be involved in the development of addiction, and that emotional alterations may compromise the effectiveness of treatment approaches in substance abuse. Nonetheless, there is a dearth of studies that have examined the experience of emotions in substance abusers, especially with regard to natural affective stimuli that are motivati...