The hypoxia inducible transcription factor (HIF) has been shown to coordinate the hypoxic response of vertebrates and is expressed in three different isoforms, HIF-1α, HIF-2α and HIF-3α. Knock down of either Hif-1α or Hif-2α in mice results in lethality in embryonic or perinatal stages, suggesting that this transcription factor is not only controlling the hypoxic response, but is also involved ...

For almost a decade, Content-Based Image Retrieval has been an active research area, yet one fundamental problem remains largely unsolved: how to measure perceptual similarity. To measure perceptual similarity, most researchers employ the Minkowski-type metric. Our extensive data-mining experiments on visual data show that, unfortunately, the Minkowski metric is not very effective in modeling p...

The zebrafish (Danio rerio) is a useful vertebrate model for use in cardiovascular drug discovery. The present study aimed to construct optimized methods for the study of intravascular lipid metabolism of zebrafish. The lipophilic dye, Oil Red O, was used to stain fasting zebrafish one to eight days post-fertilization (dpf) and to stain 7-dpf zebrafish incubated in a breeding system containing ...

Segmentation of speech into its corresponding phones has become very important issue in many speech processing areas such as speech recognition, speech analysis, speech synthesis, and speech database. In this paper, for accurate segmentation in speech recognition applications, we introduce Distinctive Phonetic Feature (DPF) based feature extraction using a twostage NN (Neural Networks) system c...

the current regulated particle metric in vehicle emissions is the total mass, while during last decade interest in number size distribution has increased. various international studies on epidemiology and toxicology have reported the adverse effect of the particle matter on public health. the unece group of experts on pollution and energy (grpe) under particle measurement program (pmp) are unde...

In order to reduce the tailpipe particulate matter emissions of Diesel engines, Diesel particulate filters (DPFs) are commonly used. Initial studies using a conductometric soot sensor to monitor their filtering efficiency, i.e., to detect a malfunction of the DPF, are presented. The sensors consist of a planar substrate equipped with electrodes on one side and with a heater on the other. It is ...

The medaka, Oryzias latipes is a useful animal model for the study of primary vasculature in vertebrate embryos. Using benzidine stain for erythroid cells, we found presumptive erythropoietic foci in the yolk sac vitellolysis zone at stage 39. These foci were present in the yolk syncytial layer, in the extravascular and vitellolysis zone from 9 days post fertilization (dpf) to 11 dpf, and then ...

PURPOSE To quantify the relationship between velocity and pressure gradient in a distal protection filter (DPF) and to determine the feasibility of modeling a DPF as a permeable surface using computational fluid dynamics (CFD). METHODS Four DPFs (Spider RX, FilterWire EZ, RX Accunet, and Emboshield) were deployed in a single tube representing the internal carotid artery (ICA) in an in vitro f...

With the aim of using an automatic speech recognition (ASR) system in practical environments, various approaches focused on noise-robustness such as noise adaptation and reduction techniques have been investigated. We have previously proposed a distinctive phonetic feature (DPF) parameter set for a noise-robust ASR system, which reduced the effect of high-level additive noise[1]. This paper des...

Duchesnea indica (Andr.) Focke has been traditionally used to treat cancer in Asian countries for centuries. In the present study, transplanted U14 cervical cancer mouse model was used to evaluate the antitumor and immunomodulatory activity of Duchesnea phenolic fraction (DPF). ELISA and RIA assay were employed to measured the serum concentration of Th1/Th2 cytokines (IL-2, IL-4, IFN-γ and TNF-...